Abstract: Herein, a kind of MOF-based mixed-matrix membrane, MIL-101@PAN, capable of removing diclofenac sodium from aqueous solution by decompression filtration, was prepared based on a stable MOF, MIL-101(Cr), and polyacrylonitrile. According to our investigations, the obtained MOF-based membranes displayed loose and porous structure with a membrane thickness of about 14 μm. Otherwise, the performance of the membranes could be significantly improved with the increase of MOF content. Specifically, when the mass ratio of MOF to polymer reaches 40% (MIL-101(Cr): PAN = 2:5), the prepared membrane MIL-101@ PAN-2 exhibits the best removal performance for diclofenac sodium, particularly achieving a removal efficiency of 95.59% for a diclofenac sodium solution with a concentration of 20 mg·L-1, and maintaining a removal efficiency above 75% even after five cycles. Furthermore, even in a mixed solution containing Na+, K+, and NH4+ at concentrations comparable to those of diclofenac sodium(20 mg·L-1), the membrane can still maintain a removal efficiency of over 90%.

Key words: MIL-101(Cr), Mixed-matrix membrane, Diclofenac sodium