Synthesis and Characterization of Magnetic Ferroferric Oxide-Mesoporous Silica Janus Nanoparticles†

doi:10.7503/cjcu20141097

Abstract

Abstract:

Superparamagnetic and surface-modified Fe₃O₄ nanoparticles were synthesized via high-temperature hydrolysis method. With the Fe₃O₄ nanoparticles as seed, silica stick grows on one side of nanoparticle via a non-classic controlled nucleation and growth method, and Janus-magnetic-mesoporous nanoparticles were achieved. The length of silica nanostick in Janus nanoparticle can be controlled by the amount of added TEOS. But the length of silica nanostick in primary growth process is limited, a secondary growth is important to increase the length of silica nanostick. Due to the mesoporous characteristic of silica nanostick, a loading and releasing experiment was conducted, and a sustained-releasing process of doxorubicin was verified.

Key words: Ferroferric oxide, Silica, Janus nanoparticle, Sustained-releasing

CLC Number:

O614.8

TrendMD:

WEI Guangyao, ZHANG Jiawei, LI Aiwu, LIU Lianqing, YANG Hai, WANG Jiping. Synthesis and Characterization of Magnetic Ferroferric Oxide-Mesoporous Silica Janus Nanoparticles^†[J]. Chem. J. Chinese Universities, 2015, 36(5): 838.

Figures/Tables 8

Fig.1 TEM image of Fe3O4 magnetic nanoparticles

Fig.2 FTIR spectrum(A) and XRD pattern(B) of Fe3O4 magnetic nanoparticles

Fig.3 Raman spectrum(A) and hysteresis loop(B) of Fe3O4 magnetic nanoparticles

Fig.4 TEM images of Fe3O4-SiO2 Janus particles in particular lengths of 200 nm(A), 300 nm(B),400 nm(C) and 400 nm(D) V(TEOS)/μL: (A) 10; (B) 20; (C) 30; (D) 40.

Fig.5 TEM images of Fe3O4-SiO2 Janus particles in particular length of 1 μm(A), 1.5 μm(B) and 2 μm(C) via a secondary growth method and of 4 μm(D) via a muti-growth methodV(TEOS)/μL: (A) 10; (B) 20; (C) 30.

Fig.6 HRTEM images of Fe3O4-SiO2 mesoporous Janus nanoparticles with enlarged view of selected area(A and the inset) and pictures of Fe3O4-SiO2 mesoporous Janus nanoparticles without(B) and with(C) magnetic field for 2 min

Fig.7 UV-Vis absorption spectra of Fe3O4-SiO2 mesoporous Janus particles(a) and Fe3O4-SiO2-DOX mesoporous Janus particles(b) in water

Fig.8 UV-Vis absorption spectra of DOX in water after magnetic separation for different timeTime/h: a. 0; b. 2; c. 4; d. 6; e. 8; f. 10.

References 27

[1]	苏鹏飞, 赵珺, 陈国. 高等学校化学学报, 2011, 32( 7), 1472- 1477
	Su P., F. , Zhao, J. , Chen, G. , Chem. J. Chinese Universities, 2011, 32( 7), 1472- 1477
[2]	王岩, 王笑英, 吕言云, 许文斌, 郭轶, 徐立. 高等学校化学学报, 2013, 34( 12), 2866- 2870
	Wang, Y. , Wang X., Y. , Lü, Y. Y. , Xu W., B. , Guo, Y. , Xu, L. , Chem. J. Chinese Universities, 2013, 34( 12), 2866- 2870
[3]	陈明洁, 熊小敏, 沈辉, 刘海峰. 高等学校化学学报, 2013, 34( 8), 1801- 1805
	Chen M., J. , Xiong X., M. , Shen, H. , Liu H., F. , Chem. J. Chinese Universities, 2013, 34( 8), 1801- 1805
[4]	Mura, S. , Nicolas, J. , Couvreur, P. , Nat. Mater., 2013, 12( 11), 991- 1003
[5]	Zhang, L. , Dong W., F. , Tang Z., Y. , Song J., F. , Xia, H. , Sun H., B. , Opt. Lett., 2010, 35( 19), 3297- 3299
[6]	Chen., W. , Pan X., L. , Bao X., H. , J. Am. Chem. Soc., 2007, 129( 23), 7421- 7426
[7]	Wang, J. , Black K. C., L. , Luehmann, H. , Li, W. , Zhang, Y. , Cai, X. , Wan, D. , Liu S., Y. , Li, M. , Kim, P. , Li Z., Y. , Wang L., V. , Liu, Y. , Xia, Y. , ACS Nano, 2013, 7( 3), 2068- 2077
[8]	洪友良, 商铁存, 靳玉伟, 杨帆, 王策. 高等学校化学学报, 2005, 26( 5), 985- 987
	Hong Y., L. , Shang T., C. , Jin Y., W. , Yang, F. , Wang, C. , Chem. J. Chinese Universities, 2005, 26( 5), 985- 987
[9]	Zhang L., Y. , Wang T., T. , Yang, L. , Liu, C. , Wang C., G. , Liu H., Y. , Wang Y., A. , Su Z., M. , Chem. Eur. J., 2012, 18( 39), 12512- 12521
[10]	Chen, Y. , Chen H., R. , Zhang S., J. , Chen, F. , Zhang L., X. , Zhang J., M. , Zhu, M. , Wu H., X. , Guo L., M. , Feng J., W. , Shi J., L. , Adv. Funct. Mater., 2011, 21( 2), 270- 278
[11]	Zhang, E. , Kircher M., F. , Koch, M. , Eliasson, L. , Goldberg S., N. , ACS Nano, 2014, 8( 4), 3192- 3201
[12]	Wang, C. , Xu C., J. , Zeng, H. , Sun S., H. , Adv. Mater., 2009, 21( 30), 3045- 3052
[13]	Jiang, S. , Chen, Q. , Tripathy, M. , Luijten, E. , Schweizer K., S. , Adv. Mater., 2010, 22( 10), 1060- 1071
[14]	Lattuada, M. , Hatton T., A. , Nano Today, 2011, 6( 3), 286- 308
[15]	Zhang Y., L. , Chen Q., D. , Xia, H. , Sun H., B. , Nano Today, 2010, 5( 5), 435- 448
[16]	Girshovitz, P. , Shaked N., T. , Light-Science & Applications, 2014, 3, e151
[17]	Gao B., R. , Wang H., Y. , Hao Y., W. , Fu L., M. , Fang H., H. , Jiang, Y. , Wang, L. , Chen Q., D. , Xia, H. , Pan L., Y. , Ma Y., G. , Sun H., B. , J. Phys. Chem. B, 2010, 114( 1), 128- 134
[18]	Feng, J. , Li, F. , Gao W., B. , Liu S., Y. , Liu, Y. , Wang, Y. , Appl. Phys. Lett., 2001, 78( 25), 3947- 3949
[19]	Su Y., H. , Ke Y., F. , Cai S., L. , Yao Q., Y. , Light-Science & Applications, 2012, 1, e14
[20]	Zhang Y., L. , Guo, L. , Wei, S. , He Y., Y. , Xia, H. , Chen Q., D. , Sun H., B. , Nano Today, 2010, 5( 1), 15- 20
[21]	Xia, H. , Wang, J. , Tian, Y. , Chen Q., D. , Du X., B. , Zhang Y., L. , He, Y. , Sun H., B. , Adv. Mater., 2010, 22( 29), 3204- 3207
[22]	Guo, L. , Jiang H., B. , Shao R., Q. , Zhang Y., L. , Xie S., Y. , Wang J., N. , Li X., B. , Jiang, F. , Chen Q., D. , Zhang, T. , Sun H., B. , Carbon, 2012, 50( 4), 1667- 1673
[23]	Yang, R. , Yu Y., S. , Xue, Y. , Chen, C. , Chen Q., D. , Sun H., B. , Opt. Lett., 2011, 36( 23), 4482- 4484
[24]	Wu, D. , Wu S., Z. , Chen Q., D. , Zhang Y., L. , Yao, J. , Yao, X. , Niu L., G. , Wang J., N. , Jiang, L. , Sun H., B. , Adv. Mater., 2011, 23( 4), 545- 549
[25]	Zhang, L. , Wang Y., S. , Yang, Y. , Zhang, F. , Dong W., F. , Zhou S., Y. , Pei W., H. , Chen H., D. , Sun H., B. , Chem. Commun., 2012, 48( 91), 11238- 11240
[26]	Huang X., L. , Teng, X. , Chen, D. , Tang F., Q. , He J., Q. , Biomaterials, 2010, 31( 3), 438- 448
[27]	Deng Y., H. , Qi D., W. , Deng C., H. , Zhang X., M. , Zhao D., Y. , J. Am. Chem. Soc., 2008, 130( 1), 28- 29