Novel Air Flow Assisted Ionization Ion Source and Its Performance on Various Types of Mass Analyzer

doi:10.3969/j.issn.0251-0790.2012.05.008

Chem. J. Chinese Universities ›› 2012, Vol. 33 ›› Issue (05): 908.doi: 10.3969/j.issn.0251-0790.2012.05.008

• Analytical Chemistry • Previous Articles Next Articles

Novel Air Flow Assisted Ionization Ion Source and Its Performance on Various Types of Mass Analyzer

HE Jiu-Ming¹, LUO Zhi-Gang¹, TANG Fei², CHEN Yi², GONG Tao², HE Jing-Jing¹, ZHANG Rui-Ping¹, WANG Xiao-Hao², ZEPER Abliz^5,1

1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China;
2. State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments and Mechanology, Tsinghua University, Beijing 100084, China

Received:2011-09-27 Online:2012-05-10 Published:2012-05-10

Abstract

Abstract: The growth of the field of ambient mass spectrometry(MS) is rapid because of its advantage on direct MS analysis with minimum or without sample pretreatment. Ion source is one of the key techniques for mass spectrometer. This paper described the advanced development of air flow assisted ionization ion source(AFAI) and its performance on various types of mass analyzer. The maximum extracting gas flow rate was improved up to 75 L/min, and the sensitivity of the AFAI was investigated with higher extracting gas flow rate. AFAI ion source was installed on various types of mass analyzer including time of flight(TOF), Q-TRAP and Q-TOF via a corresponding modularized interface. Therefore, the full mass scan, product ion scan, precursor ion scan, neutral loss scan and accurate mass measurement would be carried out for ambient MS analysis with AFAI. The advanced development of the AFAI would promote its applications.

Key words: Air flow assisted ionization, Mass spectrometry, Modularization, Fast real-time analysis

CLC Number:

O657

TrendMD:

HE Jiu-Ming, LUO Zhi-Gang, TANG Fei, CHEN Yi, GONG Tao, HE Jing-Jing, ZHANG Rui-Ping, WANG Xiao-Hao, ZEPER Abliz. Novel Air Flow Assisted Ionization Ion Source and Its Performance on Various Types of Mass Analyzer[J]. Chem. J. Chinese Universities, 2012, 33(05): 908.

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Novel Air Flow Assisted Ionization Ion Source and Its Performance on Various Types of Mass Analyzer

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