高等学校化学学报

高等学校化学学报 ›› 2011, Vol. 32 ›› Issue (5): 1054.

• 研究论文 • 上一篇    下一篇

基质固相分散提取桃儿七根中鬼臼毒苷和异鬼臼苦酮

金永日2,时晓磊3,李绪文2,赵学忠4,张慕淳1   

  1. 1. 吉林大学中日联谊医院泌尿外科, 长春 130033;
    2. 化学学院, 长春 130012;
    3. 军需科技学院, 长春 130062;
    4. 第一医院心血管内科, 长春 130021
  • 收稿日期:2010-12-13 修回日期:2011-01-19 出版日期:2011-05-10 发布日期:2011-04-11
  • 通讯作者: 张慕淳;赵学忠 E-mail:zhangmuchun@sohu.com;zhxzh@medmail.com.cn
  • 基金资助:

    国家“十一五”技术支撑计划项目(批准号： 2006BAI14B01)资助.

Matrix Solid Phase Dispersion for the Extraction of Podophyllotoxin Glucoside and Isopicropodophyllone from Roots of Sinopodophyllum emodi(Wall.)

JIN Yong-Ri2, SHI Xiao-Lei3, LI Xu-Wen2, ZHAO Xue-Zhong4*, ZHANG Mu-Chun1*   

  1. 1. Department of Urology,  China\|Japan Union Hospital, Jilin University,  Changchun 130033, China;
    2. College of Chemistry, Jilin University,  Changchun 130012, China;
    3. College of Quartermaster Technology, Jilin University,  Changchun 130062, China;
    4. Department of Cardiology, First Hospital of Jilin University, Changchun 130021, China
  • Received:2010-12-13 Revised:2011-01-19 Online:2011-05-10 Published:2011-04-11
  • Contact: ZHANG Mu-Chun;ZHAO Xue-Zhong E-mail:zhangmuchun@sohu.com;zhxzh@medmail.com.cn
  • Supported by:

    国家“十一五”技术支撑计划项目(批准号： 2006BAI14B01)资助.

PDF (PC)

被引次数

12

摘要： 采用基质固相分散提取桃儿七根中的鬼臼毒苷和异鬼臼苦酮，并用高校液相色谱法进行了测定，选择硅胶为分散剂和甲醇为洗脱剂对鬼臼毒苷进行提取，硅藻土为分散剂和甲醇为洗脱剂对异鬼臼苦酮进行提取，与回流提取法相比，提取率较高。

关键词: 基质固相分散法, 桃儿七根, 鬼臼毒苷, 异鬼臼苦酮

Abstract: A fast and simple extraction procedure based on the matrix solid-phase dispersion was proposed for the extraction of two kinds of lignans including Podophyllotoxin gluoside and isopicropodophylloneas from the dried roots of Sinopodophyllum emodi wall.. The compounds were determined by High performance liquid chromatography. The main parameters that affect extraction yields, such as type of dispersant, type of clean-up absorbent, were examined and optimized. Compared with reflux extraction, the proposed method is simpler, faster and more efficient.

Key words: Matrix solid phase dispersion, roots of sinopodophyllum emodi Wall., Podophyllotoxin gluoside, isopicropodophylloneas

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