高等学校化学学报

高等学校化学学报 ›› 2011, Vol. 32 ›› Issue (4): 857.

• 研究论文 • 上一篇    下一篇

Hg(Ⅱ)与法莫替丁和阴离子表面活性剂三元混配物的共振瑞利散射、二级散射和倍频散射光谱及其分析应用

陈佩丽,刘绍璞,刘忠芳,胡小莉   

  1. 西南大学化学化工学院, 发光及实时分析教育部重点实验室, 重庆 400715
  • 收稿日期:2010-07-05 修回日期:2010-09-06 出版日期:2011-04-10 发布日期:2011-03-09
  • 通讯作者: 胡小莉 E-mail:peili211@swu.edu.cn
  • 基金资助:

    国家自然科学基金(批准号: 20875078)和发光与实时分析重庆市重点实验室基金(批准号: 2006CA8006)资助.

Resonance Rayleigh Scattering, Second-order Scattering and Frequency Doubling Scattering Spectra of Ternary Mixed Ligand Complex of Hg(Ⅱ)\|famotidine and Anionic Surfactant and Their Analytical Applications

CHEN Pei-Li, LIU Shao-Pu, LIU Zhong-Fang, HU Xiao-Li*   

  1. Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China
  • Received:2010-07-05 Revised:2010-09-06 Online:2011-04-10 Published:2011-03-09
  • Contact: HU Xiao-Li E-mail:peili211@swu.edu.cn
  • Supported by:

    国家自然科学基金(批准号: 20875078)和发光与实时分析重庆市重点实验室基金(批准号: 2006CA8006)资助.

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被引次数

28

摘要： 在pH 5.9 NaAc-HAc的缓冲溶液中，法莫替丁(FMTD)与Hg(II)形成五元环螯合阳离子([Hg(FMTD)]2+)，再进一步与十二烷基硫酸钠(SLS)，十二烷基苯磺酸钠(SDBS)和十二烷基磺酸钠(SDS)等阴离子表面活性剂(AS)反应形成1: 1: 2的三元混配物([Hg(FMTD)(AS)2]). 此时，引起体系共振瑞利散射(RRS)、二级散射(SOS)和倍频散射(FDS)的显著增强. 最大的散射波长位于345~352 nm (RRS法)、544 nm (SOS法) 和352 nm (FDS法)，3种散射强度(?I)的顺序均为SLS>SDS>SDBS，在一定范围内?I与FMTD的浓度成良好的线性关系，检出限为3.3~3.9 ng/mL (RRS法)、14.6 ~ 16.3 ng/mL (SOS法)和7.0 ~ 8.5 ng/mL (FDS法). 据此提出了灵敏度高、选择性好、快速准确测定FMTD的光散射新方法. 适用于注射液、血清和尿样中FMTD含量的测定. 文中探讨了[Hg(FMTD)(AS)2]的形成对吸收和RRS光谱的影响及引起RRS增强的原因.

关键词: 法莫替丁, 汞, 阴离子表面活性剂, 共振瑞利散射, 二级散射, 倍频散射

Abstract: In pH 5.9 NaAc-HAc buffer medium, famotidine (FMTD) reacted with Hg (II) to form chelate cation ([Hg(FMTD)]2+), which further reacted with anionic surfactants (AS) such as sodium dodecylsulfate (SLS), sodium dodecylbenzene sulfonate (SDBS) and sodium dodecylsulphate (SDS) to form ternary mixed coordination compound([Hg(FMTD)(AS)2]). As a result, the resonance Rayleigh scattering (RRS), second-order scattering (SOS) and frequency doubling scattering (FDS) were enhanced greatly. Their maximum wavelengths were located at 345~352 nm, 544 nm and 352 nm, respectively. The three scattering intensity (ΔI) were proportional to the FMTD concentration in a certain range and the detection limits were 3.3~3.9 ng/mL (RRS method), 14.6 ~ 16.3 ng/mL (SOS method) and 7.0 ~ 8.5 ng/mL (FDS method). Based on it, a sensitive, good selective, simple, rapid and new method had been proposed to determine FMTD. It can be applied to determine FMTD in injection, serum and urea sample. The formative mechanism of[Hg(FMTD)(AS)2] was discussed, the effects of formation of [Hg(FMTD)(AS)2] on absorption and RRS spectra were investigated, the reasons of enhancement for RRS was also discussed.

Key words: famotidine, Hg (II), anionic surfactant, resonance Rayleigh scattering, second-order scattering, frequency doubling scattering

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