高等学校化学学报 ›› 2009, Vol. 30 ›› Issue (7): 1431.

• 研究快报 • 上一篇    下一篇

阿魏酸丙三酯的分子内协同抗氧化作用研究

姚同伟1, 杜立波2, 杨屹1, 徐元超1, 贾宏瑛2, 刘扬2   

  1. 1. 北京化工大学理学院, 北京 100029;
    2. 中国科学院化学研究所分子动态与稳态结构国家重点实验室, 北京 100190
  • 收稿日期:2009-03-20 出版日期:2009-07-10 发布日期:2009-07-10
  • 通讯作者: 刘扬, 男, 博士, 研究员, 主要从事生命科学中的自由基化学研究. E-mail: yliu@iccas.ac.cn
  • 基金资助:

    国家“八六三”计划(批准号: 2007AA10Z352)资助.

Studies on Intermolecular Synergistic Antioxidant Activity in Glyceride Tri-ferulate

YAO Tong-Wei1, DU Li-Bo2, YANG Yi1, XU Yuan-Chao1, JIA Hong-Ying2, LIU Yang2*   

  1. 1. School of Science, Beijing University of Chemical Technology, Beijing 100029, China;
    2. State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
  • Received:2009-03-20 Online:2009-07-10 Published:2009-07-10
  • Contact: LIU Yang. E-mail: yliu@iccas.ac.cn
  • Supported by:

    国家“八六三”计划(批准号: 2007AA10Z352)资助.

摘要:

设计并合成了一个包含3个阿魏酸抗氧化功能基团的新型抗氧化剂分子——阿魏酸丙三酯, 并以阿魏酸单体分子作对照从自由基清除效果与动力学反应活化能两个角度对比分析了阿魏酸丙三酯与DPPH·反应间的协同抗氧化作用.

关键词: 自由基; 抗氧化剂; 阿魏酸; 活化能; 协同效应

Abstract:

A glyceride containing three ferulic groups was first synthesized in order to investigate intermolecular synergistic antioxidant activity. The antioxidant activity was evaluated via a radical-scavenging reaction of DPPH˙ radical. Although the scavenging capacities of both antioxidants, ferulic acid and glyceride tri-ferulate, were roughly equal, the apparent activation energy(Ea) of 19.50 kJ/mol for glyceride tri-ferulate is obviously lower than that of 28.80 kJ/mol for ferulic acid. The synergistic effect on Ea was further explained by a parallel π-π-stacking interaction.

Key words: Free radical; Antioxidant; Ferulic acid; Activation energy; Synergistic effect

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