高等学校化学学报 ›› 2006, Vol. 27 ›› Issue (4): 622.

• 研究论文 • 上一篇    下一篇

芘基丁酸键合硅胶固定相对含π电子物质的高效液相色谱分离研究

余琼卫, 屈粒, 何海波, 冯钰锜   

  1. 武汉大学化学与分子科学学院, 武汉 430072
  • 收稿日期:2005-06-14 出版日期:2006-04-10 发布日期:2006-04-10
  • 通讯作者: 冯钰锜(1962年出生), 男, 博士, 教授, 博士生导师, 主要从事分离材料的研究. E-mail: yqfeng@public.wh.hb.cn
  • 基金资助:

    国家自然科学基金(批准号: 20475040)资助

Separation of Solutes Containing π-Electron on  Pyrenebutyric  Acid-bonded Silica Stationary Phase by HPLC

YU Qiong-Wei, QU Li, HE Hai-Bo, FENG Yu-Qi*   

  1. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China
  • Received:2005-06-14 Online:2006-04-10 Published:2006-04-10
  • Contact: FENG Yu-Qi,E-mail: yqfeng@public.wh.hb.cn

摘要:

通过芘基丁酸键合硅胶固定相对含π电子物质的分离研究, 考察了该固定相的色谱性能. 结果表明, 该固定相不仅具有疏水作用和电荷转移性能, 还具有很强的平面识别能力, 可很好地分离烷基苯、 稠环芳烃及取代硝基苯等各种含π电子物质, 且在pH 3.5~7.0 时化学稳定性能良好, 硅醇基效应得到了很好的抑制, 可有效地用于碱性化合物的分离分析.

关键词: 芘基丁酸; 固定相; 稠环芳烃; 取代硝基苯; 高效液相色谱

Abstract:

The chromatographic performance of pyrenebutyric acid-bonded silica phase was evaluated by studying the separation of solutes containing π-electron. The results show that the PYB not only have the hydrophobicity and charge-transfer ability but also have the planar recognized ability, and could separate well such solutes containing  π-electron  as polycyclic aromatic hydrocarbon and some nitroaromatic hydrocarbons. The stationary phase has a high stability at a pH value between 3.5 and 7.0. The silanophilic activity of the PYB was weakened because of the existence of the amide group in the packing. It can be efficiently used for the analysis of basic compounds.

Key words: Pyrenebutyric acid; Stationary phase; Polycylic aromatic hydrocarbon;  Nitroaromatic hydrocarbon; HPLC

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