高等学校化学学报 ›› 2005, Vol. 26 ›› Issue (2): 235.

• 研究简报 • 上一篇    下一篇

单嘧磺隆原药组成的定性和定量分析

范志金1, 钱传范2, 艾应伟3, 陈俊鹏1, 李正名1   

  1. 1. 南开大学元素有机化学国家重点实验室,天津 300071;
    2. 中国农业大学理学学院,农业部农药化学及农药使用技术重点开放实验室,北京 100094;
    3. 四川大学生命科学学院,成都 610065
  • 收稿日期:2004-01-20 出版日期:2005-02-10 发布日期:2005-02-10
  • 通讯作者: 范志金(1968年出生),男,博士,副教授,主要从事农药学研究.E-mail:fanzj@nankai.edu.cn E-mail:fanzj@nankai.edu.cn
  • 基金资助:

    国家重点基础研究发展计划项目(批准号:2003CB114406);国家自然科学基金(批准号:20107003)资助

Identification and Quantification Analysis of Active Ingredient and Main Impurities in Monosulfuron

FAN Zhi-Jin1, QIAN Chuan-Fan2, AI Ying-Wei3, CHEN Jun-Peng1, LI Zheng-Ming1   

  1. 1. State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China;
    2. Key Laboratory of Pesticide Chemistry & Application Technology of Ministry of Agriculture, College of Science, China Agricultural University, Beijing 100094, China;
    3. College of Life Science, Sichuan University, Chengdu 610065, China
  • Received:2004-01-20 Online:2005-02-10 Published:2005-02-10

关键词: 单嘧磺隆原药, 磺酰脲类除草剂, 高压液相色谱-质谱联用仪

Abstract: Monosulfuron was identified by m.p., IR, NMR, MS, UV and HPLC/MS analysis in this study, the results indicate that, the active ingredient of monosulfuron was N-[2'-(4'-methyl) pyrimidyl]-2-nitrobenzensulfonylurea, it's main impurities were 2-amino-4-methylpryrimidine, 2-nitrobenzensulfonamide and ethyl 2-nitrobenzensulfonyl carbamate. The method of reverse HPLC analysis for active ingredient and main impurities in monosulfuron were established by using 250 mm× 4.6 mm stainless column of ODS 5 μm with V(CH3OH)∶V(H2O)= 60∶40 containing H3PO4 ( pH 3.0) as a mobile phase, 0.8 mL/min of flow rate, 225 nm as UV determination wave length. All components of monosulfuron which consisted of more than 0.1% were quantitated.

Key words: Monosulfuron, Sulfonylurea herbicide, HPLC/MS

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