高等学校化学学报 ›› 2004, Vol. 25 ›› Issue (11): 2010-2012.

• 研究快报 • 上一篇    下一篇

傅里叶变换红外光谱法用于体表无创性检测乳腺肿瘤的研究

李庆波1, 徐智2, 徐怡庄1, 张元福1, 张能维2, 王立新2, 孙学军3, 张莉1, 王凡1, 杨丽敏1, 赵莹4, 任予3, 刘智1, 翁诗甫1, 周维金1, 吴瑾光1   

  1. 1. 北京大学化学与分子工程学院, 稀土材料化学及应用国家重点实验室, 北京100871;
    2. 北京大学第三医院, 北京100083;
    3. 西安交通大学第一医院, 西安710061;
    4. 中国科学院化学研究所, 北京100080
  • 收稿日期:2004-05-21 出版日期:2004-11-24 发布日期:2004-11-24
  • 基金资助:

    国家重点基础研究发展规划项目(批准号:2002CCA01900);国家自然科学基金(批准号:30371604,50203001,20171004);教育部博士学科点基金资助.

Application of Fourier Transform Infrared Spectroscopy to Non-invasive Detection of Breast Tumor in vivo and in situ

LI Qing-Bo1, XU Zhi2, XU Yi-Zhuang1, ZHANG Yuan-Fu1, ZHANG Neng-Wei WANG Li-Xin2, SUN Xue-Jun2, ZHANG Li3, WANG Fan1, YANG Li-Min1, ZHAO Ying REN Yu1, LIU Zhi4, WENG Shi-Fu3, ZHOU Wei-Jin1, WU Jin-Guang1   

  1. 1. The State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China;
    2. The Third Hospital, Peking University, Beijing 100083, China;
    3. The First Hospital of Xi′an Jiaotong University, Xi′an 710061, China;
    4. Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China
  • Received:2004-05-21 Online:2004-11-24 Published:2004-11-24

关键词: FTIR, 中红外光纤, 乳腺肿瘤, 在体原位无创检测

Abstract: The non-invasive detection of breast tumor in vivo and in situ was first investigated by FTIR fiber optics technique. The experiment result indicates that there are significant differences between the spectra of skin outside breast tumor and normal breast tissues in the peak position and relative intensity. The in vivo FTIR spectroscopy can provide the information concerning whether the suspected tissue is cancerous or not. This recent result means that in situ FTIR spectroscopic method with fiber optics can be developed as a non-invasive, rapid and in vivo technique for early breast tumor detection.

Key words: FTIR, Mid-IR fiber optics, Breast tumor, Non-invasive detection in vivo and in situ

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