高等学校化学学报

高等学校化学学报 ›› 2002, Vol. 23 ›› Issue (7): 1264.

• 研究论文 • 上一篇    下一篇

聚二甲基硅氧烷微流控芯片的紫外光照射表面处理研究

孟斐, 陈恒武, 方群, 朱海霖, 方肇伦   

  1. 浙江大学化学系, 微分析系统研究所, 杭州 310028
  • 收稿日期:2001-08-08 出版日期:2002-07-24 发布日期:2002-07-24
  • 通讯作者: 陈恒武(1947年出生),男,博士,教授,博士生导师,从事微流控分析研究.E-mail:hwchen@mail.hz.zj.cn E-mail:hwchen@mail.hz.zj.cn
  • 基金资助:

    国家自然科学基金(批准号:20299030,20299031)

Surface Modification of Poly(dimethylsiloxane)-fabricated Microfluidic Chip by UVRadiation

MENG Fei, CHEN Heng-Wu, FANG Qun, ZHU Hai-Lin, FANG Zhao-Lun   

  1. Institute of Microanalytical System, Department of Chemistry, Zhejiang University, Hangzhou 310028, China
  • Received:2001-08-08 Online:2002-07-24 Published:2002-07-24

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被引次数

123

摘要： 研究了紫外光化学表面改性对聚二甲基硅氧烷(PDMS)微流控芯片的片基间粘接力及毛细管通道电渗流性能的影响.PDMS片基经紫外光射照后,粘接力增强,可实现PDMS芯片的永久性封合,同时亲水性得到改善,通道中的电渗流增大.与文献报道的等离子体表面处理方法比较,采用紫外光表面处理,设备简单,操作方便,耗费少,是一种简单易行的聚二甲基硅氧烷芯片表面处理方法.

关键词: 微流控分析系统, 聚二甲基硅氧烷芯片, 光化学表面处理

Abstract: UVradiation was applied to modify the surface of poly(dimethylsiloxane)(PDMS) fabricated microfluidic replica. After the surface of PDMSwas irradiated by a 6 Wlow pressure mercury lamp, the adhesion between PDMSplates was significantly strengthened, and the PDMSplates were irreversibly sealed when the irradiated surfaces were brought into contact. Hydrophilic behavior of PDMSreplica was improved due to the photochemical reaction induced by UVradiation, resulting in a significant increase in the electroosmotic flow of buffers filled in the microchannels of the chip. Compared with the reported procedures using oxygen plasma pretreatment, the present approach allows one to easily modify the surface of PDMSplates using very simple and cheap equipment available in analytical laboratory.

Key words: Microfluidic analytical system, PDMS chip, Photochemical surface modification

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