高等学校化学学报

高等学校化学学报 ›› 2001, Vol. 22 ›› Issue (1): 78.

• 研究简报 • 上一篇    下一篇

5-(S)-烷氧基-3,4-二卤-2(5H)-呋喃酮在二甲基甲酰胺中的Michael加成-消除反应

李学强1, 波林1, 王凤荣1, 陈庆华2, 王志丹2   

  1. 1. 宁夏大学化学科学与工程系, 银川 750021;
    2. 北京师范大学化学系, 北京 100875
  • 收稿日期:2000-01-15 出版日期:2001-01-24 发布日期:2001-01-24
  • 通讯作者: 李学强(1962年生),男,硕士,副教授,主要从事有机合成和有机分析研究.E-mail:Lixq@nxu.edu.cn E-mail:Lixq@nxu.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:29672004);宁夏回族自治区自然科学基金资助

Michael Addition-elimination Reactions of Chiral-5-Alkoxy-3,4-dihalo-2(5H)-Furanones in DMF

LI Xue-Qiang1, GONG Bo-Lin1, WANG Feng-Rong1, CHEN Qing-Hua2, WANG Zhi-Dan2   

  1. 1. Department of Chemistry & Chemical Engineering, Ningxia University, Yinchuan 750021, China;
    2. Department of Chemistry, Beijing Normal University, Beijing 100875, China
  • Received:2000-01-15 Online:2001-01-24 Published:2001-01-24

PDF (PC)

被引次数

5

关键词: 二甲基甲酰胺, Michael加成-消除反应, 金属钠, 5-烷氧基-2(5H)-呋喃酮

Abstract: In this paper, we report the tandem Michael addition-elimination reactions of chiral 5-alkoxy-3,4-dihalo-2(5H)-furanones with DMF by the catalyst of metal sodium. The optically pure 5-(S)-alkoxy-4-N,N-dimethyl-3-halo-2(5H)-furanones 6a-6d were identified on the basis of their analytical data, such as [α]D20, UV, IR, 1H NMR, 13C NMR, MSand elemental analysis.

Key words: Dimethyl formamide, Michael addition-elimination, Sodium, Chiral-5-alkoxy-3,4-dihalo-2(5H)-furanones

中图分类号: 

TrendMD: