高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 73.

• Analytical Sciences • 上一篇    下一篇

Study on the Nitroxide-linked Naphthalene as a Probe for Hydroxyl Radicals

YANG Xiao-Feng, GUO Xiang-Qun, LIU Jian-Li, MAO Yu-Xia, ZHAO Yi-Bing   

  1. Department of Chemistry and the Key Laboratory of Analytical Science of MOE, Xiamen University, Xiamen 361005
  • 出版日期:2000-12-31 发布日期:2000-12-31
  • 通讯作者: GUO Xiang-Qun
  • 基金资助:

    The work was supported by Natural Science Foundation of Fujian Province (D9920001) and National Educi Committee of China.

Study on the Nitroxide-linked Naphthalene as a Probe for Hydroxyl Radicals

YANG Xiao-Feng, GUO Xiang-Qun, LIU Jian-Li, MAO Yu-Xia, ZHAO Yi-Bing   

  1. Department of Chemistry and the Key Laboratory of Analytical Science of MOE, Xiamen University, Xiamen 361005
  • Online:2000-12-31 Published:2000-12-31
  • Contact: GUO Xiang-Qun
  • Supported by:

    The work was supported by Natural Science Foundation of Fujian Province (D9920001) and National Educi Committee of China.

PDF (PC)

被引次数

1

摘要：

Reactive oxygen species (ROS),such as superoxide radical (O2-)and hydroxyl radical (OH), are thought to be involved in the action of many toxins and several human diseases. Among the various radicals,the hydroxyl radical is presumed to play a central role due to its strong activity. Several methods have been developed to detect hydroxyl radicals. Among them, one of the most commonly used is ESR method. Because of a high-cost instrument, this method is not suitable for routine analysis. Another method is aromatic hydroxylation. Though this method is highly sensitive, the multiple hydroxylation products make the quantitative detection of hydroxyl radical complex.

Abstract:

Reactive oxygen species (ROS),such as superoxide radical (O2-)and hydroxyl radical (OH), are thought to be involved in the action of many toxins and several human diseases. Among the various radicals,the hydroxyl radical is presumed to play a central role due to its strong activity. Several methods have been developed to detect hydroxyl radicals. Among them, one of the most commonly used is ESR method. Because of a high-cost instrument, this method is not suitable for routine analysis. Another method is aromatic hydroxylation. Though this method is highly sensitive, the multiple hydroxylation products make the quantitative detection of hydroxyl radical complex.

TrendMD: