高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 72.
• Analytical Sciences • 上一篇 下一篇
MAO Yu-Xia1, GUO Xiang-Qun1, CHEN Rong2, ZHENG Wei-Yun2
MAO Yu-Xia1, GUO Xiang-Qun1, CHEN Rong2, ZHENG Wei-Yun2
摘要:
Condenced aromatics in the environment are harmful to the organisms for its carcinogenesis. When it is metabolized in organism, several kinds of radicals and active oxygen intermediates such as superoxide radical anion (O2-) and hydrogen peroxide would produce. These active oxygen intermediates may cause DNA damage. Catalase (CAT), a major endogenous antioxidant, presents in all aerobes and has a crucial function in protecting living organisms against the unrestrained reactivity of H2O2. When the amount of H2O2 generated in the body increase due to the outside factors, the activity of the CAT will be induced to rise significantly. Thus the activity of CAT, as a biomarker, may reflect die exist of condensed aromatics in the environment. Now there are many methods to detect CAT, such as spectrophotometric methods, titration,electrochemical process, volumetric analysis, but they are not sensitive enough for direct detection of CAT in marine biological samples.
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