高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 498.

• Biological Analysis • 上一篇    下一篇

Development of a Quartz Piezoelectric Crystal Immunosensor Based on Self-Assembled Monolayer

Fung Y. S., Wong Y. Y.   

  1. Department of Chemistry, The University of Hong Kong, Pohfulam Road, Hong Kong, SAR, China
  • 出版日期:1999-12-31 发布日期:1999-12-31

Development of a Quartz Piezoelectric Crystal Immunosensor Based on Self-Assembled Monolayer

Fung Y. S., Wong Y. Y.   

  1. Department of Chemistry, The University of Hong Kong, Pohfulam Road, Hong Kong, SAR, China
  • Online:1999-12-31 Published:1999-12-31

摘要:

A novel method of immobilizing antibodies on piezoelectric crystal (P/Z) sensor was developed based on self-assembled monolayer (SAM) using alkanethiols for immunosensing. The assembly of SAMs on metal surface is relatively easy and they are closely packed, well ordered and stable in ambient conditions. Thus,SAMs are good candidates for immobilizing biomolecules onto ultrathin layers.

Abstract:

A novel method of immobilizing antibodies on piezoelectric crystal (P/Z) sensor was developed based on self-assembled monolayer (SAM) using alkanethiols for immunosensing. The assembly of SAMs on metal surface is relatively easy and they are closely packed, well ordered and stable in ambient conditions. Thus,SAMs are good candidates for immobilizing biomolecules onto ultrathin layers.

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