高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 492.

• Biological Analysis • 上一篇    下一篇

Study of the Reaction between Nucleic Acids and Tb-BPMPHD-CTMAB Complex and its Analytical Application

WU Xia, YANG Jing-He, CAO Xi-Hui, SUN Li-Mei, HUANG Fang   

  1. Department of Chemistry, Shandong University, Jinan 250100, P. R. China
  • 出版日期:1999-12-31 发布日期:1999-12-31
  • 基金资助:

    Supported by Natural Science Foundations of China and Shandong Province, the Research Laboratory of SEDC of Analytical Science for Material and Life Chemistry (Xiamen University) and Laboratory for Colloid and Interface Chemistry of State Education Commission (Shandong University).

Study of the Reaction between Nucleic Acids and Tb-BPMPHD-CTMAB Complex and its Analytical Application

WU Xia, YANG Jing-He, CAO Xi-Hui, SUN Li-Mei, HUANG Fang   

  1. Department of Chemistry, Shandong University, Jinan 250100, P. R. China
  • Online:1999-12-31 Published:1999-12-31
  • Supported by:

    Supported by Natural Science Foundations of China and Shandong Province, the Research Laboratory of SEDC of Analytical Science for Material and Life Chemistry (Xiamen University) and Laboratory for Colloid and Interface Chemistry of State Education Commission (Shandong University).

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摘要：

The direct use of the fluorescence emission properties of nucleic acids in the investigation of their biological properties is limited, whereas the use of metal complexes as fluorescence probe to study nucleic acids has increased remarkbly. Recently we found that the Tb-l,6-bi(1'-phenyl-3'-methyl-5'-pyrazolone-4'-)hezane-dione(BPMPHD)-trimethyl am-monium bromide(CTMAB) complex can be used as a sensitive fluorescence probe for the determination of nucleic acids.

Abstract:

The direct use of the fluorescence emission properties of nucleic acids in the investigation of their biological properties is limited, whereas the use of metal complexes as fluorescence probe to study nucleic acids has increased remarkbly. Recently we found that the Tb-l,6-bi(1'-phenyl-3'-methyl-5'-pyrazolone-4'-)hezane-dione(BPMPHD)-trimethyl am-monium bromide(CTMAB) complex can be used as a sensitive fluorescence probe for the determination of nucleic acids.

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