高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 348.

• Molecular Spectroscopy • 上一篇    下一篇

A Fluorescence Probe Study on the Chiral Microenvironment of Bile Salt Organized Media

XIE Jian-Wei1, ZHANG Shu-Zhen2, LIU Chang-Song2   

  1. 1. Beijing Institute of Pharmacology & Toxicology, Academy of Military Medical Science, Beijing 100850, P. R. China;
    2. Department of Chemistry, Shanxi University, Taiyuan, 030006, P. R. China
  • 出版日期:1999-12-31 发布日期:1999-12-31

A Fluorescence Probe Study on the Chiral Microenvironment of Bile Salt Organized Media

XIE Jian-Wei1, ZHANG Shu-Zhen2, LIU Chang-Song2   

  1. 1. Beijing Institute of Pharmacology & Toxicology, Academy of Military Medical Science, Beijing 100850, P. R. China;
    2. Department of Chemistry, Shanxi University, Taiyuan, 030006, P. R. China
  • Online:1999-12-31 Published:1999-12-31

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摘要：

Bile salt aggregation in aqueous solution has been an active area of research, with primary emphasis on the physiological role of bile salts in lipid solubilization. More recently, bile salt media has attracted attention as an alternative to conventional micellar reagents for separations and luminescence analysis, especially for applications in chiral separations. In this study, pyrene and chiral molecular l,1'-bi-2-naphthol as fluorescence probe were used to study chiral microenvironment of bile salt organized media.

Abstract:

Bile salt aggregation in aqueous solution has been an active area of research, with primary emphasis on the physiological role of bile salts in lipid solubilization. More recently, bile salt media has attracted attention as an alternative to conventional micellar reagents for separations and luminescence analysis, especially for applications in chiral separations. In this study, pyrene and chiral molecular l,1'-bi-2-naphthol as fluorescence probe were used to study chiral microenvironment of bile salt organized media.

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