高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 338.

• Molecular Spectroscopy • 上一篇    下一篇

Study on Inclusion Complexes of Amoxicillin with Dimethyl-β-Cyclodextrin by Fluorimetry

MA Li-Hua, CHEN Liang   

  1. Test and Analysis Center of Shanxi University, Taiyuan, 030006, P. R. China
  • 出版日期:1999-12-31 发布日期:1999-12-31

Study on Inclusion Complexes of Amoxicillin with Dimethyl-β-Cyclodextrin by Fluorimetry

MA Li-Hua, CHEN Liang   

  1. Test and Analysis Center of Shanxi University, Taiyuan, 030006, P. R. China
  • Online:1999-12-31 Published:1999-12-31

摘要:

It is estimated that at least 10% of orally administered drugs can form inclusion complexes with CDs and nearly half of them can be improved in the aspects of their physical and chemical properties. CDs have been used in drugs either for complexes or as auxiliary additives such as solubilizers, diluents or tablet ingredients to improve the solubility, stability and bioavailability of drugs, deodorize and detoxicate drugs,and control release of drugs.

Abstract:

It is estimated that at least 10% of orally administered drugs can form inclusion complexes with CDs and nearly half of them can be improved in the aspects of their physical and chemical properties. CDs have been used in drugs either for complexes or as auxiliary additives such as solubilizers, diluents or tablet ingredients to improve the solubility, stability and bioavailability of drugs, deodorize and detoxicate drugs,and control release of drugs.

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