高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 328.

• Molecular Spectroscopy • 上一篇    下一篇

Spectrophotometric Determination of Norfloxacin Using Alizarin Red

LI Hua-Kan, WANG Min, FENG Li   

  1. Department of Chemistry, Jinzhou Medical College, Jinzhou, 12l001, P. R. China
  • 出版日期:1999-12-31 发布日期:1999-12-31

Spectrophotometric Determination of Norfloxacin Using Alizarin Red

LI Hua-Kan, WANG Min, FENG Li   

  1. Department of Chemistry, Jinzhou Medical College, Jinzhou, 12l001, P. R. China
  • Online:1999-12-31 Published:1999-12-31

摘要:

Norfloxacin is effective antibiotics against a broad range of vegetative Gram-positive and Gram-negative bacteria. This drug is widely used as preservation in pharmaceutical formulations. In the past, norfloxacin products were determinated by using various methods, Such as spectrophotometry, HPLC and fluorescence. This paper describes an investigation of the charge transfer reaction between norfloxacin as donor and alizarin red as acceptor, leading to the determination of norfloxacin and the application of the method to suppository.

Abstract:

Norfloxacin is effective antibiotics against a broad range of vegetative Gram-positive and Gram-negative bacteria. This drug is widely used as preservation in pharmaceutical formulations. In the past, norfloxacin products were determinated by using various methods, Such as spectrophotometry, HPLC and fluorescence. This paper describes an investigation of the charge transfer reaction between norfloxacin as donor and alizarin red as acceptor, leading to the determination of norfloxacin and the application of the method to suppository.

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