高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 227.

• Chromatography and Separation Sciences • 上一篇    下一篇

Size Characterization of Pharmaceutical Microspheres by Flow Field-Flow Fractionation

Myeong Hee Moon, Keum-mi Kim   

  1. Department of Chemistry, Kangnung National University, Kangnung 210-702, Korea
  • 出版日期:1999-12-31 发布日期:1999-12-31

Size Characterization of Pharmaceutical Microspheres by Flow Field-Flow Fractionation

Myeong Hee Moon, Keum-mi Kim   

  1. Department of Chemistry, Kangnung National University, Kangnung 210-702, Korea
  • Online:1999-12-31 Published:1999-12-31

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摘要：

Flow field flow fractionation (FIFFF), one of the subtechniques in FFF family, is a separation technique that can be applied for the separation and characterization of particulate materials, biological macromolecules, and water soluble polymers. Separation in FIFFF is carried out in an empty channel by the interaction of applied field from an external source with flow. Retention of particles or macromolecules in FIFFF is governed by the relative protrusion of sample materials to the differential flow streamlines. Thus in FIFFF, particle size can be readily calculated from the experimental fractogram by theory or calibration.

Abstract:

Flow field flow fractionation (FIFFF), one of the subtechniques in FFF family, is a separation technique that can be applied for the separation and characterization of particulate materials, biological macromolecules, and water soluble polymers. Separation in FIFFF is carried out in an empty channel by the interaction of applied field from an external source with flow. Retention of particles or macromolecules in FIFFF is governed by the relative protrusion of sample materials to the differential flow streamlines. Thus in FIFFF, particle size can be readily calculated from the experimental fractogram by theory or calibration.

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