高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 137.

• Electroanalytical Chemistry • 上一篇    下一篇

Determination of Trace Levels of Medroprogesterone Acetate in the Presence of KIO3 by Adsorptive-Catalytic Stripping Voltammetry

KANG Xiao-Feng, SONG Jun-Feng   

  1. Institute of Analytical Science, Northwest University, Xian 710069, P. R. China
  • 出版日期:1999-12-31 发布日期:1999-12-31

Determination of Trace Levels of Medroprogesterone Acetate in the Presence of KIO3 by Adsorptive-Catalytic Stripping Voltammetry

KANG Xiao-Feng, SONG Jun-Feng   

  1. Institute of Analytical Science, Northwest University, Xian 710069, P. R. China
  • Online:1999-12-31 Published:1999-12-31

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摘要：

A adsorptive-catalytic stripping voltammetry has received considerable attention in recent years. However,the method has been used to only a limited extent of inorganic ions. And no method for organic compounds has been reported so far. In this paper,the adsorptive properties of Medroprogesterone Acetate(MPA) on a hanging mercury electrode and the mechanism of catalytic wave in the presence of KIO3 were studied. A new sensitive adsorptive-catalytic stripping voltammetry for the determination of MPA is proposed based on the combination of adsorptive accumulation of MPA with the regeneration of the reactant MPA by the homogeneous catalytic reaction between KIO3 and intermediate radical HMPA formed in the reduction process of MPA. The dual amplification resulting from adsorptive-catalytic effects produces excellent sensitivity. The adsorptive-catalytic stripping process of MPA differs from inorganic ions in catalytic mechanism. The catalytic current is produced by the chemical reaction between KIO3 and HMPA, instead of the catalytic current of complexation produced at the mercury electrode surface.

Abstract:

A adsorptive-catalytic stripping voltammetry has received considerable attention in recent years. However,the method has been used to only a limited extent of inorganic ions. And no method for organic compounds has been reported so far. In this paper,the adsorptive properties of Medroprogesterone Acetate(MPA) on a hanging mercury electrode and the mechanism of catalytic wave in the presence of KIO3 were studied. A new sensitive adsorptive-catalytic stripping voltammetry for the determination of MPA is proposed based on the combination of adsorptive accumulation of MPA with the regeneration of the reactant MPA by the homogeneous catalytic reaction between KIO3 and intermediate radical HMPA formed in the reduction process of MPA. The dual amplification resulting from adsorptive-catalytic effects produces excellent sensitivity. The adsorptive-catalytic stripping process of MPA differs from inorganic ions in catalytic mechanism. The catalytic current is produced by the chemical reaction between KIO3 and HMPA, instead of the catalytic current of complexation produced at the mercury electrode surface.

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