高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (6): 879.

• 研究快报 • 上一篇    下一篇

生物素-亲和素系统在压电免疫传感器中质量放大作用研究

裴仁军, 胡继明, 刘栗加, 胡毅, 曾云鹗   

  1. 武汉大学分析测试科学系, 武汉 430072
  • 收稿日期:1998-12-31 出版日期:1999-06-24 发布日期:1999-06-24
  • 通讯作者: 胡继明
  • 作者简介:裴仁军,男,27岁,博士研究生.
  • 基金资助:

    国家自然科学基金(批准号:39670218)资助课题

Mass Amplification of Biotin-avidin System in Piezoelectric Immunosensor

PEI Ren-Jun, HU Ji-Ming, LIU Li-Jia, HU Yi, ZENG Yun-E   

  1. Department of AnalysisMeasurement Science, Wuhan University, Wuhan, 430072
  • Received:1998-12-31 Online:1999-06-24 Published:1999-06-24

PDF (PC)

被引次数

13

摘要： 生物素-亲和素系统(BiotinAvidinSystem,BAS)是70年代后期迅速发展起来的一种新型生物放大系统,具有高灵敏度、高特异性以及简便、经济、快速等优点,在现代生物免疫学领域中已得到广泛的应用[1].

关键词: 压电免疫传感器, 生物素-亲和素系统, 质量放大免疫检测

Abstract: Piezoelectric immunosensor has a vast future of applications in biochemistry and clinical medicine. Mass amplification immune assay could improve the detection sensitivity remarkably and would enlarged the application fields remarkably. In this paper, we first developed amplification immune assay of piezoelectric immunosensor using biotinavidin system. The mass adsorbed on the crystal surface was amplified and the detection sensitivity of the sensor improved remarkably so that the detection range was enlarged and the detection low limit of linear range was declined.

Key words: Piezoelectric immunosensor, Biotin-avidin system, Mass amplification immune assay G)

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