高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (2): 199.

• 论文 • 上一篇    下一篇

HELP法在中草药分析中的应用研究──冬虫夏草的化学成分测定

龚范1, 彭源贵2, 崔卉1, 梁逸曾1, AlexanderK.M.Leung3, Foo-timChau3   

  1. 1. 湖南大学化学化工学院, 化学计量学与化学传感技术研究所;
    2. 湖南省中医药研究院中药研究所, 长沙 410082;
    3. 香港理工大学不对称合成开放实验室
  • 收稿日期:1998-06-08 出版日期:1999-02-24 发布日期:1999-02-24
  • 通讯作者: 梁逸曾
  • 作者简介:龚范,男,29岁,博士.
  • 基金资助:

    国家自然科学基金

HELP Applied to Traditional Chinese Medicine Analysis Determination of Components of Cordyceps Sinensis

GONG Fan1, PENG Yuan-Gui2, CUI Hui1, LIANG Yi-Zeng1, Alexander K.M.Leung3, Foo-timChau3   

  1. 1. College of Chemistry and Chemical Engineering, Institute of Chemometrics and Chemical Sensing Technology, Hunan University, Changsha, 10082;
    2. Institute of Materia Medica, Hunan Academy of Tradition Chinese Medicine&Materia Medica, Chang sha, 410082;
    3. Open Laboratory of A symmetric Sythesis, Departmemt of Applied Biology and Chemical Technology, Hong Kong Poly technic University, Kowloon, Hong Kong
  • Received:1998-06-08 Online:1999-02-24 Published:1999-02-24

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摘要： 基于直观推导式演进特征投影(HELP)法,对冬虫夏草子座和虫体分别进行了多组分同时定性定量测定.结果表明,HELP法能减少样本提取分离的步骤,降低色谱分离条件的要求,提高检测准确度.联用色谱检测与化学计量学解析法相结合将为复杂中草药分析提供一种全新手段.

关键词: 直观推导式演进特征投影法, 冬虫夏草, 多组分分析

Abstract: The multicomponent qualitative and quantitative analysis of Stroma and Caterpillar body of Cordyceps sinensis were carried out by Heuristic Evolving Latent Projection(HELP) method. The procedure for resolving the twoway chromatogram/spetrum data obtained from the hyphenated instruments with HELP was developed in detail. It showed that HELP method could be used to examine the purity of chromatographic peaks, resolve overlapping peaks and finally obtain the pure chromatographic profiles and spectra for all the chemical components in the studied system. The separation ability of chromatography can be greatly improved. Moreover, the accuracy of qualitative and quantitative results could also be enhanced by means of this method. HELP method could be a promising method to the simultaneous multicomponent analysis for traditional chinese medicine.

Key words: Heuristic evolving latent projections, Cordyceps sinensis, Multicomponent analysis

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