一系列阳离子性卟啉化合物的基质辅助激光解吸质谱行为

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (12): 1858.

一系列阳离子性卟啉化合物的基质辅助激光解吸质谱行为

刘淑清¹, 孙浩然¹, 王仁章¹, 徐吉庆^1,2

1. 吉林大学化学系, 长春 130023;
2. 南京大学配位化学国家重点实验室, 南京 210093

收稿日期:1999-04-16 出版日期:1999-12-24 发布日期:1999-12-24
通讯作者: 徐吉庆
作者简介:刘淑清,女,27岁,博士研究生.
基金资助:
国家自然科学基金(批准号:29733090,29803003);南京大学配位化学国家重点实验室资助课题

Application of Matrix-assisted Laser Desorption/Ionization-time of Flight-mass Spectrometry in Characterizing a Series of Cationic Porphyrins

LIU Shu-Qing¹, SUN Hao-Ran¹, WANG Ren-Zhang¹, XU Ji-Qing^1,2

1. Department of Chemistry, Jilin University, Changchun 130022, China;
2. The State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, China

Received:1999-04-16 Online:1999-12-24 Published:1999-12-24

摘要/Abstract

摘要： 应用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF-MS)研究了一系列阳离子性卟啉化合物的质谱行为.结果表明,阳离子性卟啉与非离子性卟啉化合物的激光解吸电离方式有明显不同.对于四-氮R基(R=甲基,乙基,丙基,苄基)吡啶基卟啉,吡啶基氮上的侧链基团(R)可明显影响该类化合物在MALDI-TOF-MS测试过程中离子形成方式;R基团的增大以及平衡阴离子半径的增大可增加平衡阴离子与卟啉环阳离子之间相互作用力的共价成分,因此在MALDI-TOF-MS测定过程中能够得到卟啉环阳离子与多个平衡阴离子结合在一起的较高质量数的离子峰.另外,还初步探讨了阳离子性卟啉化合物的激光解吸电离机理.

关键词: 阳离子性卟啉, 基质辅助激光解吸飞行时间质谱, 解吸电离机理

Abstract: The matrix-assisted laser desorption/ionization-time of flight-mass spectrometric behavior of a series of cationic porphyrins was studied. The results showed the desorption/ionization ways of cationic porphyrins were different from those of non-ionic porphyrins. The space volume of the side chain groups of the porphyrins apparently affects the desorption/ionization mechanism of the formation of ions. The larger the space volume of the side chain groups and anions is, the larger the portion of the covalence is between the porphyrin cycle cation and the balance anions. As a result, the higher mass ion peaks formed by the porphyrin cycle cation combined with more anions appeared in the MALDI-TOF mass spectra. The desorption/ionization mechanisms of the cationic porphyrins were also discussed in this paper.

Key words: Cationic porphyrins, Matrix-assisted laser desorption/ionization-time of flight-mass spectrometry, Desorption/ionization mechanisms

中图分类号:

O657.6

TrendMD:

刘淑清, 孙浩然, 王仁章, 徐吉庆. 一系列阳离子性卟啉化合物的基质辅助激光解吸质谱行为. 高等学校化学学报, 1999, 20(12): 1858.

LIU Shu-Qing, SUN Hao-Ran, WANG Ren-Zhang, XU Ji-Qing . Application of Matrix-assisted Laser Desorption/Ionization-time of Flight-mass Spectrometry in Characterizing a Series of Cationic Porphyrins. Chem. J. Chinese Universities, 1999, 20(12): 1858.