高等学校化学学报

高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (10): 1589.

• 论文 • 上一篇    下一篇

1-苯甲酰基-1-甲硫基甲醇与硫脲和芳胺的反应研究

邹建平, 刘现军, 许勇, 陆忠娥   

  1. 苏州大学化学系, 苏州, 215006
  • 收稿日期:1997-09-17 出版日期:1998-10-24 发布日期:1998-10-24
  • 通讯作者: 邹建平,男,35岁,副教授.
  • 作者简介:邹建平,男,35岁,副教授.
  • 基金资助:

    江苏省教育委员会自然科学基金(批准号:95094)资助课题.

Studies on the Reaction of 1-Benzoyl-1-methylthiomethanol with Thioureas and Arylamines

ZOU Jian-Ping, LIU Xian-Jun, XU Yong, LU Zhong-E   

  1. Department of Chemistry, Suzhou University, Suzhou, 215006
  • Received:1997-09-17 Online:1998-10-24 Published:1998-10-24

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摘要： 1-苯甲酰基-1-甲硫基甲醇(2)与硫脲(3a)和芳基取代硫脲(3b-3i)在弱酸性条件下回流反应1h,得到5-苯基咪唑啉-2-硫酮-4-酮(4a)和1-芳基-5-苯基咪唑啉-2-硫酮-4-酮(4b-4i),产率72%～89%.而化合物2与芳胺(5a-5f)在弱碱性条件下回流反应3h,则得到2-芳胺基-2-甲硫基苯乙酮(6a-6f),产率为64%～88%.

关键词: 1-苯甲酰基-1-甲硫基甲醇, 1-芳基-5-苯基咪唑啉-2-硫酮-4-酮, 2-芳胺基-2-甲硫基苯乙酮

Abstract: 1-Benzoyl-1-methylthiomethanol(2) can react with thiourea(3a) and arylthioureas( 3b_3i ) in the slightly acidic medium to afford 5-phenylimidazolidine-2-thione-4-one(4a) and 1-aryl-5-phenylimidazolidine-2-thione-4-ones(4b_4i). On the other hand, when compound 2 was refluxed with arylamines in the slightly alkaline medium, 2-arylamino-2-methylthioacetophenones(6a_6f) can be obtained. Their structures are confirmed by X-ray, IR, 1H NMR, MSand elemental analysis.

Key words: 1-Benzoyl-1-methylthiomethanol, 1-Aryl-5-phenylimidazolidine-2-thione-4-one, 2-Arylamino-2-methylthioacetophenone

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