高等学校化学学报

高等学校化学学报 ›› 1995, Vol. 16 ›› Issue (12): 1903.

• 论文 • 上一篇    下一篇

芳香醛与3-甲基-1-苯基-5-吡唑啉酮固相缩合反应的研究

李晚陆1,2, 麻洪1,2, 王永梅1,2, 孟继本1,2   

  1. 1. 南开大学化学系, 天津, 300071;
    2. 兰州大学应用化学重点实验室
  • 收稿日期:1994-12-01 修回日期:1995-05-28 出版日期:1995-12-24 发布日期:1995-12-24
  • 通讯作者: 孟继本
  • 作者简介:李晓陆,男,35岁,讲师.
  • 基金资助:

    国家自然科学基金

Studies on Solid State Condesation Reaction of Aromatic Aldehydes and 3-Methyl-1-phenyl-5-pyrazolone

LI Xiao-Liu1,2, MA Hong1,2, WANG Yong-Mei1,2, MENG Ji-Ben1,2   

  1. 1. Department of Chemistry, Nankai University, Tianjin, 300071
  • Received:1994-12-01 Revised:1995-05-28 Online:1995-12-24 Published:1995-12-24

PDF (PC)

被引次数

22

关键词: 芳香醛, 3-甲基-1-苯基-5-毗哇琳酮, 固相缩合反应

Abstract: In this paper,the condensation reactions of substituted benzaldehydes with 3 methyl-1-phenyl-5-pyrazolone at room temperature and with Lewis acid cataly;is in solid state and in melted state were investigated, and two products,4,4'-arylidene-bis-(3-methyl-1-phenyl-5-pyrazolone) 2 and 4-arylidene-3-methyl-1-phenyl-5-pyrazolone l ,were prepared in high yields respectively.This solid state condensation, which had highly reactive selectivity and efficiency, might be a feasible synthetic method. In solution the bis-pyrazolone products 2 would be inverted into the mono-pyrazolone products 1 and pyrazolone,and the equilibrium of the interconversion between the two products 1 and 2 was reached gradually。In solid state the products 2 existed in enolic form, and could coordinated with copper ion easily.

Key words: Aromatic aldehyde, 3-Methyl-1-pheny1-5-pyrazolone, Solid state condensation

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