高等学校化学学报 ›› 1993, Vol. 14 ›› Issue (4): 508.

• 研究论文 • 上一篇    下一篇

2-氨基-5-取代基4-噻唑基膦酸酯的质谱研究

焦献云, 胡秉方   

  1. 北京农业大学应用化学研究所, 北京 100094
  • 收稿日期:1992-05-19 修回日期:1992-11-23 出版日期:1993-04-24 发布日期:1993-04-24
  • 通讯作者: 焦献云

A Study of Mass Spectrometry of 2-Amino-5-substituted-4-thiazolyl Phosphonates

JIAO Xian-Yun, HU Bing-Fang   

  1. Institute of Applied Chemistry, Beijing Agricultrual University, Beijing, 100094
  • Received:1992-05-19 Revised:1992-11-23 Online:1993-04-24 Published:1993-04-24

摘要: 本文对一系列2-氨基-5-取代基-4-噻唑基膦酸酯进行了质谱研究,发现2-氨基-5-取代基-4-噻唑基膦酸酯的膦酰基中的烷基在碎裂过程中产生了一种新的γ-烷基重排反应,并且讨论了这类化合物的质谱碎裂行为,用电子轰击碰撞活化质量分析离子动能谱(EI-CA-MIKES)和高分辨精确质量测量技术(AMMT)作了进一步的研究。

关键词: &gamma, -烷基重排, EI-CA-MIKES, 噻唑基膦酸酯

Abstract: The fragmentation characteristic of a series of recently developed 2-amino-5-substituted-4-thiazolyl-phosphonates is studied by using electron impact (EI), electron impact-collision activity-mass analysed ion kinetic energy spectrometry (EI-CA-MIKES) and accurate mass measurment (AMM) techniques.It is found that a new type of γ-alkyl rearrangement has occured as evidenced by the'pres-ence of a molecular daughter ion of ethylated thiazole ring(m/z 203).The molecular parent and daughter ions have been fully identified by their unsaturation, accurate ion mass and elementary constitution.The fragmentation pathway is portrayed in a scheme(see Fig.2)

Key words: γ-Alkyl rearrangment, EI-CA-MIKES, Thiazolyl, Phosphonate

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