高等学校化学学报 ›› 1993, Vol. 14 ›› Issue (10): 1427.

• 研究论文 • 上一篇    下一篇

反胶团相转移法提取青霉素G的研究

吴子生, 贾颖萍, 褚莹, 王玉洁, 刘沛妍, 马占芳   

  1. 东北师范大学化学系, 长春 130024
  • 收稿日期:1992-12-25 修回日期:1993-03-25 出版日期:1993-10-24 发布日期:1993-10-24
  • 通讯作者: 吴子生, 男, 55岁, 教授.
  • 作者简介:吴子生, 男, 55岁, 教授.
  • 基金资助:

    国家自然科学基金

Studies on the Phase Transfer Extraction of Penicillin G by Reverse Micelles

WU Zi-Sheng, JIA Ying-Ping, CHU Ying, WANG Yu-Jie, LIU PeiYan, MA Zhan-Fang   

  1. Department of Chemistry, Northeast Normal University, Changchun, 130024
  • Received:1992-12-25 Revised:1993-03-25 Online:1993-10-24 Published:1993-10-24

摘要: 报道了非蛋白质类活性物质青霉素G在反胶团相转移提取中的特性和机理.结果表明,青霉素G在CTAB/正辛醇:氯仿(4:1,V/V)反胶团体系中的相转移提取为离子对静电作用与胶团溶解机理;在室温及pH值5~8的条件下,提取率在90%以上,且保持了青霉素的稳定性.

关键词: 反胶团, 相转移, 青霉素G

Abstract: This paper reports the extraction properties and mechanisms of a non-protein active matter penicillin Gby reverse micelles using the phase transfer technique for the first time.It is shown that the mechanisms of the phase transfer extraction of penicillin Gusing CTAB/n-octanol : chloroform(4 : 1) reverse micellar system are ion-pairing electrostatic interactions and micellar solubilisation.It is also shown that the extraction is above 90% in the pHrange from 5 to 8 in which penicillin Gis stable at room temperature.

Key words: Reverse micelle, Phase transfer, Penicillin G

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