高等学校化学学报 ›› 1993, Vol. 14 ›› Issue (10): 1380.

• 研究论文 • 上一篇    下一篇

三氟乙酸酐催化的Friedel-Crafts酰化反应——4-乙基-2,5-二甲氧基苯基烷基酮的合成

彭红, 赵成学, 龚跃法   

  1. 华中理工大学化学系, 武汉 430074
  • 收稿日期:1992-11-22 修回日期:1993-03-18 出版日期:1993-10-24 发布日期:1993-10-24
  • 通讯作者: 赵成学
  • 作者简介:彭红, 女, 26岁, 硕士, 助教.

Friedel-Crafts Acylation Reactions Catalyzed by Trifluoroacetic Anhydride-Synthesis of 4-Ethyl-2,5-dimethoxyphenyl Alkyl Ketones

PENG Hong, ZHAO Cheng-Xue, GONG Yue-Fa   

  1. Department of Chemistry, I Iuazhong University of Science and Technology, Wuhan, 430074
  • Received:1992-11-22 Revised:1993-03-18 Online:1993-10-24 Published:1993-10-24

摘要: 本文报道了在三氟乙酸酐催化下的Friedel-Crafts酰化反应,即用8种不同取代基的脂肪酸与2-乙基-1,4-二甲氧基苯的酰化反应合成了相应的4-乙基-2,5-二甲氧基苯基烷基酮,并用IR、UV、NMR及MS进行了结构鉴定,同时讨论了该反应的规律.

关键词: 三氟乙酸酐, Friedel-Crafts酰化反应, 4-乙基-2, 5-二甲氧基苯基烷基酮

Abstract: The title compounds were synthesized through the acylation of 2-ethyl-1, 4-dimethoxybenzene 1 by eight different aliphatic carboxylic acids using trifluoroacetic anhydride as the catalyst.The eight new ketonevs were characterized by IR,NMR,UVand MSspectrometry.

Key words: Trifluoroacetic anhydride, Friedel-Crafts acylation reaction, 4-ehtyl-2,5-dimethoxy-phenyl alkyl ketone

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