高等学校化学学报

高等学校化学学报 ›› 1992, Vol. 13 ›› Issue (5): 623.

• 论文 • 上一篇    下一篇

Nephthea属软珊瑚中19-羟基甾醇Nephalsterol A及B的结构测定

王贵阳生1, 李凤英1, 曾陇梅1, 马立斌2, 涂光忠2   

  1. 1. 中山大学化学系, 广州, 510275;
    2. 北京微量化学研究所
  • 收稿日期:1991-08-03 出版日期:1992-05-24 发布日期:1992-05-24
  • 通讯作者: 曾陇梅
  • 基金资助:

    国家自然科学基金

Structure Determination of Nephalsterol A and B with 19-hydroxy Group from Soft Corals Nephthea

WANG Guiyang-sheng1, LI Feng-ying1, ZENG Long-mei1, MA Li-bin2, TU Guang-zhong2   

  1. 1. Department of Chemistry, Zhongshan University, Guangzhou, 510075;
    2. Beijing Microchemical Institute, Beijing
  • Received:1991-08-03 Online:1992-05-24 Published:1992-05-24

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摘要： 从南海软珊瑚Nephtheaalbida及N.tiexieralverseveldt中分离到2个含19-羟基的多羟基甾醇NephalsterolA(1)及B(2),通过波谱方法测定了1及2的结构依次为:24-亚甲基-胆甾-3β,5α,6β,19-四醇及24-亚甲基-胆甾-5-烯-3β,7β,19-三醇。

关键词: 软珊瑚, 多羟基甾醇, 核磁共振谱

Abstract: Two 19-hydroxylated sterols, name ne phalsterd-A (1) and B (2) were isolated from the soft corals, Nephthea albida and Nephthea tiexieral verseveldt collected off Xisha and Nansha Islands respectively.On the basis of one and two dimensional NMR and other spectroscopy methods, the structures of 1 and 2 were characterized as 24-methylene-cholestan-3β,5α,6β,19-tetrol and 24-methylene-cholestan-5-ene-3β, 7β, 19-triol respectively.1 is an unknown compound.The structure of 2 is identical with the sterols which was isolated from the soft coral Litophyton viridis by M.Bortolotto.The 1H and 13C NMR data of 1 and 2 were first assigned from the 1H-1H and 13C-1H COSY and COLOC spectra in this paper.

Key words: Soft corals, Polyhydroxylated sterols, Nephthea albida, Nephthea tiexieral verse-veldt, NMR spectra

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