高等学校化学学报

高等学校化学学报 ›› 1991, Vol. 12 ›› Issue (8): 1130.

• 论文 • 上一篇    下一篇

大孔吸附树脂对尿毒症和烧伤毒血症血浆中分子物质体外吸附的研究

郭贤权1, 于占如1, 何丹1, 史秀萍1, 何炳林1, 吴小兵2, 肖应庆2, 王铁丹2   

  1. 1. 南开大学高分子化学研究所, 天津, 300071;
    2. 中国人民解放军第一军医大学, 广州
  • 收稿日期:1990-08-05 出版日期:1991-08-24 发布日期:1991-08-24
  • 通讯作者: 郭贤权

Studies on the Adsorption of Middle Molecular Substances from the Plasma of Uremic Patients and Severe Burnt Patients in Vitro

Guo Xian-quan1, Yu Zhan-ru1, He Dan1, Shi Xiu-ping1, He Bing-lin1, Wu Xiao-bing2, Xiao Ying-qing2, Wang Tie-dan2   

  1. 1. Institute of Polymer Chemistry, Nankai University, Tianjin, 300071;
    2. The First Medical College of the PLA, Guangzhou
  • Received:1990-08-05 Online:1991-08-24 Published:1991-08-24

PDF (PC)

被引次数

7

摘要： 研究了大孔吸附树脂对尿毒症和烧伤毒血症患者血浆中分子物质的体外吸附,用SephadexG15柱层析法对血浆中分子物质进行吸附前、后的组分分析,并进行了血浆模拟灌流实验,观察中分子物质的清除率,初步探讨了大孔吸附树脂孔结构对中分子物质的吸附机理。

关键词: 大孔吸附树脂, 中分子物质, 尿毒症, 烧伤毒血症

Abstract: It was studied that the middle molecular substances (MMS) were removed with macrop-orous resins from the plasma of uremic patients and severe burnt patients in vitro. The MMS were analyzed with Sephadex G15. The simulated plasma-perfusion was carried out. The efficiency of the clearance of the MMS was investigated. The mechanism of adsorption of the MMS by macroporous resins was discussed. It is helpful for finding and preparing a way to treat the patients with hemoperfu-sion.

Key words: Macroporous adsorption resin, Middle molecular substance, Uremia, Severe burn tox-aemia

TrendMD: