高等学校化学学报

高等学校化学学报 ›› 1988, Vol. 9 ›› Issue (6): 637.

• 论文 • 上一篇    下一篇

两性药物土霉素的传感电极及其选择性规律

姚守拙, 肖俊, 聂利华   

  1. 湖南大学化工系新材料研究所
  • 收稿日期:1987-01-21 出版日期:1988-06-24 发布日期:1988-06-24
  • 通讯作者: 姚守拙
  • 基金资助:

    中国科学院基金

Amphoteric Terramycin Sensitive Electrodes and Selectivities

Yao Shouzhuo, Shiao Jun, Nie Lihua   

  1. Department of Chemical Engineering, Hunan University, Ghangsha
  • Received:1987-01-21 Online:1988-06-24 Published:1988-06-24

PDF (PC)

被引次数

6

摘要： 用离子选择性电极测定药物,研究甚多,其中大都是生物碱、季铵等类碱性药物,与非水滴定等法相比、优点并不显著,至于抗生素类药物,常用微生物法分析,缺点很多,本文报告土霉素的阳离子型与阴离子型电极,探讨了选择性规律,电极在pH1.6～3.2与pH8.0～11.0分别响应含质子化二甲胺基的土霉素一价阳离子与含离解B环烯醇基的土霉素一价阴离子,1gKij与季铵离子势及诱导效应指数有良好的线性关系,符合1gKij=a+bI-cZ/R,极限值7.07。

关键词: 土霉素传感电极, 土霉素测定, 电极选择性

Abstract: Electrodes sensitive to cationic or anionic terramycin were constructed using, terramycinium silicotungstate, TPB, DPAand cetyltribctylammonium terramycina-te as electroactive materials. The terramycinium (terramycinate) sensitive elec-trode responds to terramycinium (terramycinate) down to 10 (40) μnol/Lover pHrange 1.6-3.2 (8.0-11.0) with a slope of ca, 57.2(-58)mV/lgC. The electrode selectivities toward quaternary ammoniums and inorganic cations are described in terms of ionic potential Z/Rand induction index I:lgKij = 9.87I-31.94Z/R + 290.44(R = 0.999) and lgKij =1.422 (Z/R)-1-3.363. (R= 0.942).

Key words: Terramycin sensitive electrode, Determination, of terramycih, trode selectlectivity

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