高等学校化学学报 ›› 1988, Vol. 9 ›› Issue (2): 203.

• 研究简报 • 上一篇    

4-羟基吲哚的合成新法

刘志滨1, 杨士英2, 朱春生2, 高济宇2   

  1. 1. 中国科学技术大学应用化学系;
    2. 南京大学化学系
  • 收稿日期:1986-09-25 出版日期:1988-02-24 发布日期:1988-02-24

A New Synthesis of 4-Hydroxyindole

Liu zhibin1, Yang Shiying2, Zhu Chunsheng2, Gao Jiyu(Kao Tsiyu)2   

  1. 1. Department of Applied Chemistry, University of Science and Technology of China, Hefei;
    2. Department of Chemistry, University of Nanjing, Nanjing
  • Received:1986-09-25 Online:1988-02-24 Published:1988-02-24

摘要: 4-羟基吲哚是合成Psilocyben(Ⅰ),Psilocn(Ⅱ)的重要中间体,(Ⅰ)是墨西哥一种山菌Psilocybe mexicana Heim的主要成份,具有强烈的生理作用,用于精神神经刺激剂,在人体内(Ⅰ)能转化为:(Ⅱ)[1]

Abstract: 4-Hydroxyindole is an important intermediate in the synthesis of psilo-cyben(Ⅰ) and psilocin(Ⅱ), Anew synthesis of 4-hydroxyindole has been accomplished. This synthetic route leaving out the decarboxylation step gives much better yield.

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