高等学校化学学报

高等学校化学学报 ›› 1986, Vol. 7 ›› Issue (11): 1008.

• 研究简报 • 上一篇    下一篇

碳苷研究(Ⅲ)-取代芳基铜锂试剂与α-氯代四-O-乙酰-D-吡喃葡萄糖的反应

蔡孟深, 董令娇, 王少农, 程铁明   

  1. 北京医科大学药学院
  • 收稿日期:1985-08-29 出版日期:1986-11-24 发布日期:1986-11-24

Studies on C-Glycosides(Ⅲ)-The Reactions Between α-O-Tetraacetyl-D-Glucopyranosyl Chloride and Lithium Diarylcuprate

Cai Mengshen, Dong Lingjiao, Wang Shaonong, Cheng Tieming   

  1. College of Pharmacy, Beijing Medical University, Beijing
  • Received:1985-08-29 Online:1986-11-24 Published:1986-11-24

PDF (PC)

摘要： 前文sup>[1]报导了Grignard试剂与α-氯代四-O-乙酰-D-吡喃葡萄糖(Ⅰ)sup>[2]反应,生成碳苷的研究。本文报导芳基铜锂试剂(Ⅱ)与(Ⅰ)偶联,合成碳苷的研究。

Abstract: The preparation of lithium diarylcuprate and the reactions between lithium diarylcupratc and α-O-tctraacetyl-D-glucopyranosyl chloride were reported,1-β-Aryl-O-tetraacetyl-D-glucopyranosc,2-hydroxy-2,3,4,6-O-tetraacctyl-D-glucal from elimination reaction of acyl glucopyranosyl chloride,and a small amount of phenol,probably from the addition of water to benzyne were isolated from the reaction mixture by column chromatography.

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