高等学校化学学报 ›› 1985, Vol. 6 ›› Issue (6): 513.

• 研究简报 • 上一篇    下一篇

多取代吡咯的合成及其性质(Ⅱ)

李葆, 张书文   

  1. 吉林师范学院化学系
  • 收稿日期:1984-02-29 出版日期:1985-06-24 发布日期:1985-06-24

Synthesis and Propertion of Polysubstitution Pyrrole

Li Bao, Zhang Shuwpn   

  1. Department of Clemistry, Jilin Teacher's College, Jilin
  • Received:1984-02-29 Online:1985-06-24 Published:1985-06-24

摘要: 前文已报导1-芳基-2-甲基-3-乙酰基-5-对氯苯基吡咯。本文用间硝基-ω-溴代苯乙酮与乙酰丙酮作用,得到1-间硝基苯基-3-乙酰基-1,4-戊二酮(1),(1)与各种不同的芳香族伯胺在冰醋酸存在下进行环合反应,生成1,2,3,5-四取代吡咯(2)至(10)。后者与氨基脲反应得到相应的缩氨脲。

Abstract: Acetylacetones were treated by m-nitro-ω-bromoacetophenones to give l-(m-nitrophenyl) -3-acetyl-1, 4-pentandiketone(1). 9 new 1-aryl-2-methyl-3-acetyl-5-(m-nitrophenyl)pyrroles (2)-(10) have been synthesized by reaction of (1)with various primary amines. Semicarbazoncs were prepared from (2)-(10).Compounds(1)-(10) and the Semicarbazoncs were reported for the first time.

TrendMD: