高等学校化学学报

高等学校化学学报 ›› 1984, Vol. 5 ›› Issue (4): 555.

• 论文 • 上一篇    下一篇

呋喃氟脲嘧啶类抗癌药物的电子结构研究

郭纯孝, 樊玉国, 刘兰英   

  1. 吉林大学化学系
  • 收稿日期:1983-04-15 出版日期:1984-10-24 发布日期:1984-10-24

The Study of Electronic Structures of Antitumor Medicine of 1-Furyl-and 1,3-Di-Furyl-5-Fluoro-Pyrimindinedione

Guo Chunxiao, Fan Yuguo, Liu Lanying   

  1. Department of Chemistry, Jilin University, Changchun
  • Received:1983-04-15 Online:1984-10-24 Published:1984-10-24

PDF (PC)

被引次数

8

摘要： 本文采用CNDO/2方法计算了呋喃氟脲嘧啶类的抗癌药物及其片断的电荷、键序、能量和偶极矩。阐明其抑癌机理与电子结构的关系。

Abstract: Charges, bond orders, energies and dipole moments of 1-Furyl-and l,3-di-Furyl-5-Fluoro-Pyrimidinedione and its fragments for antitumor medicine have been calculated by using CNDO/2 method.It is further clarified by the results of the calculation that there exists certain relation between restraining cancer mechanism and electronic structures of medicine.

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