高等学校化学学报

高等学校化学学报 ›› 1984, Vol. 5 ›› Issue (1): 133.

• 研究简报 • 上一篇    下一篇

一氰乙基化β-二酮的合成及其异构化(Ⅱ)

黄化民1, 李葆2, 战永复2, 沙德有2   

  1. 1. 吉林大学化学系;
    2. 吉林师范学院化学系
  • 收稿日期:1982-09-20 出版日期:1984-02-24 发布日期:1984-02-24

MONOCYANOETHYL-β-DIKETONES AND THEIR ISCMERIZATION(Ⅱ)

Huang Huamin1, Li Bao2, Zhan Yongfu2, Sha Deyou2   

  1. 1. Department of chemistry, Jilin University, changchun;
    2. Department of chemistry, Jilin Teacher's College, Jilin
  • Received:1982-09-20 Online:1984-02-24 Published:1984-02-24

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摘要： 前文已报道,β-二酮类与丙烯腈反应,我们分离出来了一氰乙基化合物,进而异构化为5,6-二取代3,4-二氢化-2(1H)吡啶酮[1]。

Abstract: β-Diketones (butyrylacetone, isobutyrylacetone, isovalerylacetone) were treated with acrylonitrile in the presence of aqueous potassium hydroxide giving monocyanoethylated-β-diketones (Ⅰ)-(Ⅲ), which by heating with HCl were isomerized to the corresponding 3,4-dihydro-2-(1H) pyridones (Ⅳ)-(Ⅵ). (Ⅰ)-(Ⅲ) were hydrolyzed to the ketoacids (Ⅶ)-(Ⅸ). semicarbazone (Ⅹ)-(ⅩⅤ) were prepared from 5-acetyl-6-methyl-3,4dihydyo-2(1H) pyridones; pyrazole(ⅩⅥ)-(ⅩⅨ) were prepared from β-diketoncids. compounds (Ⅰ)-(ⅩⅪ) were reported for the first time.

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