高等学校化学学报 ›› 1981, Vol. 2 ›› Issue (4): 514.

• 论文 • 上一篇    下一篇

改变云芝多糖的化学结构提高其抑瘤活性的研究

张翼伸, 李治平   

  1. 东北师范大学生物系
  • 收稿日期:1980-12-27 出版日期:1981-12-24 发布日期:1981-12-24

PROMOTION OF TUMOR INHIBITORY ACTIVITY STUDIES ON CORIOLAN BY CHEMICAL STRUCTURAL MODIFICATION

Zhang Yishen, Li Zhiping   

  1. Department of Biology, Northeastern Normal University, Changchun
  • Received:1980-12-27 Online:1981-12-24 Published:1981-12-24

摘要: 本文将长白山野生云芝子实体提取的多糖,用选择性氧化和还原及部分水解的方法,切断其β(1—6)糖苷键,明显提高了云芝多糖的抑瘤活性。此外,未脱色的云芝多糖抑瘤活性较脱色者高。

Abstract: Cleavage of the β(l-6) glucosidic linkage of cariolan by a method of selective oxidation, reduction and partial hydrolysis resulted in a significant promotion of its tumor inhibitory activity.It was found also that there was a decrease of tumor inhibitory activity of cariolan from natural source in the process of decolorization.

TrendMD: