关键词: 质子耦合电子转移, 多重手性开关, 电响应, 电致酸/碱

Abstract: In this study，a chiral aniline structure was introduced into the Rhodol (3’-amino-6’-hydroxyspiro[2-benzofuran-3,9’-xanthene]-1-one) derivative main molecule，which exhibits pH (acid and base)-responsive color changes. Then，based on the proton-coupled electron transfer mechanism，a novel electrically responsive multiple chiroptical switching system was constructed by integrating the functional Rhodol derivative with electro-acid/base molecules. Controlled by suitable voltages，this system could switch among three circular dichroism absorption states reversibly: in the visible light range，no circular dichroism signal at the initial state，positive circular dichroism signal under a significant positive voltage，and negative circular dichroism signal under a considerable negative voltage. More importantly，all the switching processes were totally reversible. This research opens a new route to achieve the development of electrically responsive multiple chiroptical switching systems，and offers an important insight on the design and application of innovative materials for multiple chiroptical switches.

Key words: Proton-coupled electron transfer, Multiple chiroptical switch, Electrically response, Electro-acid/base