高等学校化学学报 ›› 2016, Vol. 37 ›› Issue (4): 669-673.doi: 10.7503/cjcu20150799

• 有机化学 • 上一篇    下一篇

果胶负载钯催化剂的制备及Suzuki反应催化性能

周文俊, 周宇, 张霞忠(), 曾彬   

  1. 内江师范学院化学化工学院, 内江 641112
  • 收稿日期:2015-10-19 出版日期:2016-04-10 发布日期:2016-03-04
  • 基金资助:
    四川省教育厅重大成果转化项目(批准号: 12ZZ012)、 四川省教育厅自然科学青年基金项目(批准号: 12ZB074,13ZB0002)和内江师范学院博士科研启动费项目(批准号: 2012B05)资助

Preparation and Suzuki Reaction Performance of Pectin-supported Palladium Catalyst

ZHOU Wenjun, ZHOU Yu, ZHANG Xiazhong*(), ZENG Bin   

  1. College of Chemistry and Chemical Engineering, Neijiang Normal University, Neijiang 641112, China
  • Received:2015-10-19 Online:2016-04-10 Published:2016-03-04
  • Contact: ZHANG Xiazhong E-mail:zhangxiazhong@163.com
  • Supported by:
    † Supported by the Sichuan Province Education Office Fostering Projects, China(No.12ZZ012), the Youth Found of Sichuan Province Education Office, China(Nos.12ZB074, 13ZB0002) and the Startup Foundation of Ph.D.Scientific Research of Neijiang Normal University, China(No.2012B05)

摘要:

以柑橘皮果胶为载体, 采用吸附法制备了果胶负载钯催化剂, 并将其应用于四苯硼钠与溴代芳烃的交叉偶联反应中. 该反应体系以聚乙二醇400(PEG 400)/H2O为反应溶剂, 三乙胺为碱, 在空气中于110 ℃反应15~60 min, 四苯硼钠中4个苯基均可顺利参与反应, 高产率地获得相应的目标化合物. 该方法具有条件温和、 反应时间短、 收率高且催化剂可循环利用等优点.

关键词: 果胶负载钯, Suzuki反应, 四苯硼钠, 溴代芳烃

Abstract:

To discover new heterogeneous palladium catalyst in organic synthesis, pectin, which was extracted form citrus peel, was used as supporter for the preparation of pectin-supported palladium catalyst. The pectin-supported palladium catalyst was applied to Suzuki cross-coupling reaction between sodium tetraphenylborate and aryl bromides. The results revealed that all four aryl groups of sodium tetraryylborate could be efficiently utilized in the Suzuki cross-coupling reactions in an atom-efficient way in the presence of Et3N as base in PEG 400/H2O at 110 ℃ in open air, providing excellent yields of the corresponding functionalized biaryls within 1 h. The present protocol has the advantages highly efficient, high yield, mild condition, short reaction time, as well as the catalyst can be recycled and reused.

Key words: Pectin supported-Pd, Suzuki reaction, Sodium tetraphenylborate, Aryl bromide

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