Chem. J. Chinese Universities ›› 2000, Vol. 21 ›› Issue (7): 1064.
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CHEN Shao-Yuan1, YU Yong-Ping2, YOU Jin-Zong2, CHEN Yao-Zu2,3
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Abstract: Two new methods for synthesis of 4β-amino-4-deoxypodophyllotoxin and 4β-amino-4'-demethyl-4-deoxypodophyllotoxin have been developed. These compounds were synthesized by reduction of the corresponding4β-anzido-podophyllotoxin derivatives with SmI2 or HCO2NH4/Pd-Cin excellent yields under mild conditions with convenient manipulation.
Key words: Podophyllotoxin, Samarium diiodide, Ammonium formate
CLC Number:
O621
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CHEN Shao-Yuan, YU Yong-Ping, YOU Jin-Zong, CHEN Yao-Zu. Two New Methods for Synthesis of 4β-Amino-4-deoxypodophyllotoxin and 4β-Amino-4'-demethyl-4-deoxypodophyllotoxin[J]. Chem. J. Chinese Universities, 2000, 21(7): 1064.
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http://www.cjcu.jlu.edu.cn/EN/Y2000/V21/I7/1064