Performance Evaluation of Home-made Glass Microfluidic Glass Chips

Abstract

Abstract: Glass microchips with different structures and functions were fabricated in our laboratory.The basic characteristic of the home-made microchips was evaluated,such as the quality of the etched microchannels,reproducibility of electrophoretic separation,and life time etc..The migration time RSD for Rhodamine B in the same or different microchannels were 2.31% or 2.44%,respectively.The column efficiency in the same glass microchip didn't declined obviously until 200 consecutive running.Compared to the glass microchip made by Micralyne,the similar separation results were obtained on both kinds of microchips.Since,the cost of the home-made glass microchips is much lower, our home-made glass microchips show a great advantage(over) the commercial microchips in terms of the performance to cost.

Key words: Glass microfluidic chips, Fabrication, Performance evaluation

CLC Number:

O657

TrendMD:

WANG Hui, HUANG Huai-Qing, DAI Zhong-Peng, GAO Yan, MA Bo, WANG Li, BAI Ji-Ling, LIN Bing-Cheng. Performance Evaluation of Home-made Glass Microfluidic Glass Chips[J]. Chem. J. Chinese Universities, 2005, 26(11): 2037.

[1]	ZHANG Shuting, AN Qi. Progress on the Design and Fabrication of High Performance Piezoelectric Flexible Materials Based on Polyvinylidene Fluoride [J]. Chem. J. Chinese Universities, 2021, 42(4): 1114.
[2]	JIANG Xiao-Tian, YIN Qi, LIU Tian-Fu, CAO Rong. Metal-organic Framework Membranes for Efficient Separation of Small Molecules and Ions [J]. Chem. J. Chinese Universities, 2020, 41(8): 1691.
[3]	LI Botian,SHAO Wei,XIAO Da,ZHOU Xue,DONG Junwei,TANG Liming. Polypyrrole Nanowire Gels Based on Templating Fabrication and Their Energy Storage and Electrochemical Sensing Properties ^† [J]. Chem. J. Chinese Universities, 2020, 41(1): 183.
[4]	GAO Miaomiao,WANG Chenglong,DOU Hongjing,XU Guoxiong. One-step Self-assembly/polymerization Fabrication and Biomedical Application of Carboplatin@Dextran Nanocarrier^† [J]. Chem. J. Chinese Universities, 2019, 40(6): 1301.
[5]	ZHOU Ying, XU Ying, LIU Lianqing, YANG Hai, WANG Jiping. Direct Femtosecond Laser Processing of Gold-silver Alloy Nanostructure by Photoreduction^† [J]. Chem. J. Chinese Universities, 2015, 36(8): 1472.
[6]	DONG Yuan-Yuan, HU Xian-Qiao, CHEN Shuang, LU Hua, HE Qiao-Hong, CHEN Heng-Wu. Fabrication of Micro/Nanofluidic Chip on Glass Substrate and Its Application for Electrokinetic Concentration of Proteins [J]. Chem. J. Chinese Universities, 2012, 33(05): 931.
[7]	LIU Ming-Yang*, ZHAO Jing-Hong, ZOU Ming-Qiang, LIU Da. Controllable Fabrication of SnO₂ Nanomaterials with Three Kinds of Morphologies and Their Application as Cataluminescence Sensor [J]. Chem. J. Chinese Universities, 2011, 32(5): 1112.
[8]	WANG Hai, CHEN Yi. Fabrication of Seamless PMMA Microfluidic Chips with and Without a Glass-fiber Mixer by Controlled in situ* Polymerization [J]. Chem. J. Chinese Universities, 2009, 30(8): 1548.
[9]	DONG Xiao-Dong^1,2, ZHANG Bai-Lin^1,2* , XIA Yong^1,2, ZHU Guo-Yi^1,2. Process Investigation of the Electrochemical Fabrication of Au Tunnel Junction with Atomic-scale [J]. Chem. J. Chinese Universities, 2008, 29(7): 1424.
[10]	SUN Wei, TANG Yue-Chao, JI Jian*. Preparation of Ordered and Porous Honeycomb Structure Film of Poly(lactic acid) with Pluronics® as the Second Component [J]. Chem. J. Chinese Universities, 2007, 28(7): 1388.
[11]	DENG Zi-Wei, CHEN Min, ZHOU Shu-Xue, YOU Bo, WU Li-Min. A Facile Approach for the Fabrication of Monodisperse Hollow Silica Spheres [J]. Chem. J. Chinese Universities, 2006, 27(10): 1795.
[12]	ZHU Ming-Zhi,, JIANG Zhuang-De, JING Wei-Xuan. Fabrication and Electrochemical Characterization of Submicrometer Interdigitated Ultramicroelectrode Arrays [J]. Chem. J. Chinese Universities, 2005, 26(5): 838.
[13]	YAN Yun-Xing, TAO Xu-Tang, XU Gui-Bao, YU Wen-Tao, YANG Jia-Xiang, WU Yong-Zhong, YU Xiao-Qiang, ZHAO Xian, JIANG Min-Hua . Synthesis, Structure and Nonlinear Optical Properties of Two-photon Photopolymerization Initiator BVPDA [J]. Chem. J. Chinese Universities, 2005, 26(3): 562.
[14]	ZHOU Xiao-Mian, DAI Zhong-Peng, LUO Yong, LIU Da-Yu WANG Hui, MAO Xiu-Li, LIN Bing-Cheng . Microfabrication and Performance of Poly(methyl methacrylate) Microfluidic Chip with Multi-channels [J]. Chem. J. Chinese Universities, 2005, 26(1): 52.
[15]	QI Heng, CHEN Tao. Study on Polymers Used in Fabrication of Biochip [J]. Chem. J. Chinese Universities, 2004, 25(S1): 49.

Performance Evaluation of Home-made Glass Microfluidic Glass Chips

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments