CJCU

Chem. J. Chinese Universities ›› 2011, Vol. 32 ›› Issue (5): 1054.

• Preface • Previous Articles     Next Articles

Matrix Solid Phase Dispersion for the Extraction of Podophyllotoxin Glucoside and Isopicropodophyllone from Roots of Sinopodophyllum emodi(Wall.)

JIN Yong-Ri2, SHI Xiao-Lei3, LI Xu-Wen2, ZHAO Xue-Zhong4*, ZHANG Mu-Chun1*   

  1. 1. Department of Urology,  China\|Japan Union Hospital, Jilin University,  Changchun 130033, China;
    2. College of Chemistry, Jilin University,  Changchun 130012, China;
    3. College of Quartermaster Technology, Jilin University,  Changchun 130062, China;
    4. Department of Cardiology, First Hospital of Jilin University, Changchun 130021, China
  • Received:2010-12-13 Revised:2011-01-19 Online:2011-05-10 Published:2011-04-11
  • Contact: ZHANG Mu-Chun;ZHAO Xue-Zhong E-mail:zhangmuchun@sohu.com;zhxzh@medmail.com.cn
  • Supported by:

    国家“十一五”技术支撑计划项目(批准号： 2006BAI14B01)资助.

PDF (PC)

Abstract: A fast and simple extraction procedure based on the matrix solid-phase dispersion was proposed for the extraction of two kinds of lignans including Podophyllotoxin gluoside and isopicropodophylloneas from the dried roots of Sinopodophyllum emodi wall.. The compounds were determined by High performance liquid chromatography. The main parameters that affect extraction yields, such as type of dispersant, type of clean-up absorbent, were examined and optimized. Compared with reflux extraction, the proposed method is simpler, faster and more efficient.

Key words: Matrix solid phase dispersion, roots of sinopodophyllum emodi Wall., Podophyllotoxin gluoside, isopicropodophylloneas

TrendMD: