Chem. J. Chinese Universities ›› 2011, Vol. 32 ›› Issue (4): 839.

• Articles • Previous Articles     Next Articles

Heat and Cold Properties of Jianghuang and Yujin Based on Brain Catecholamine Metabolic Profiling

WU Hong-Wei*, LI Hong-Mei, TANG Li-Ying, ZHANG Dong, YANG Hong-Jun, HUANG Lu-Qi*   

  1. Institute of Chinese Materia Medica, Chinese Academy of Chinese Medical Sciences, Beijing 100700, China
  • Received:2010-08-02 Revised:2010-09-21 Online:2011-04-10 Published:2011-03-09
  • Contact: HUANG Lu-Qi;WU Hong-Wei E-mail:huangluqi@263.net;whw9905012@163.com
  • Supported by:

    国家“九七三”计划项目(批准号: 2006CB504701)资助.

Abstract: Jianghuang and Yujin,as the rhizome and tuberous root of Curcuma longa L.,are used as two medicine in Traditional Chinese Medicine(TCM). It was believed Jianghuang has warm properties and Yujin has cool properties in TCM. To compare and confirm the different effect of Jianghuang and Yujin, HPLC-MS method for the quantitative determination of 7 catecholamines in brain samples was developed. And Principal Component Analysis(PCA) was processed to analyze the catecholamine metabolic profiling.The results suggest Heat-Syndrome model and Cold-Syndrome model can be distingushed by catecholamine metabolic profiling. Jianghuang and Yujin has different effect for the Heat and Cold Syndrome model based on Brain catecholamines Metabolic Profiling.

Key words: Catecholamines Metabolic Profiling, Jianghuang, Yujin, Heat and Cold properties

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