Synthesis and Herbicidal Activities of Novel 1,2,4-Triazolinone Derivatives

Chem. J. Chinese Universities

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Synthesis and Herbicidal Activities of Novel 1,2,4-Triazolinone Derivatives

WANG Lei, TANG Mi, LI Wen-Ming, LI Yong-Hong, WANG Su-Hua, LI Zheng-Ming*

State Key Laboratory of Elemento-organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin 300071, China

Received:2007-10-24 Revised:1900-01-01 Online:2008-07-10 Published:2008-07-10
Contact: LI Zheng-Ming

Abstract

Abstract: Several triazolinone compounds such as amicarbazone, azafenidin, sulfentrazone and carfentrazone-ethyl have been developed as herbicides. They are considered to be environment-benign and have a broader application. In order to search for novel 1,2,4-triazolinone derivatives with high herbicidal activities, pyrimidinyl and phenylsulfonyl were introduced to the leading structure. On the basis of the principle of molecular design and structure-activity relationship, twenty-one new 1,2,4-triazolinone derivatives bearing either pyrimidinyl or phenylsulfonyl were designed and synthesized. Their structures were identified by ¹H NMR, MS and elemental analysis. The results of preliminary biological activity tests show that some compounds displayed a herbicidal activity at 1.5 kg/ha.

Key words: 1,2,4-Triazolinone, Pyrimidinyl, Phenylsulfonyl, Herbicidal activity

CLC Number:

O626.41

TrendMD:

WANG Lei, TANG Mi, LI Wen-Ming, LI Yong-Hong, WANG Su-Hua, LI Zheng-Ming*. Synthesis and Herbicidal Activities of Novel 1,2,4-Triazolinone Derivatives[J]. Chem. J. Chinese Universities, doi: .

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Synthesis and Herbicidal Activities of Novel 1,2,4-Triazolinone Derivatives

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