Chem. J. Chinese Universities

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Isolation and Identification of a New Triterpene from Neonauclea sessilifolia

KANG Wen-Yi1,2*, ZHANG Bai-Rang1, HAO Xiao-Jiang2   

    1. Institute of Natural Products, Henan University, Kaifeng 475004, China;
    2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China
  • Received:2007-03-20 Revised:1900-01-01 Online:2007-11-10 Published:2007-11-10
  • Contact: KANG Wen-Yi

Abstract: Neonauclea sessilifolia belongs to Rubiaceae and its chemical constituents and pharmacological investigations were seldom reported. To search the active constituents of the plant, the ethanol of the dried stem of Neonauclea sessilifolia was separated via reflux with ethanol, then the crude product was extracted with ethyl acetate and n-butanol in sequence. The ethyl acetate extract was further isolated by silica gel and Sephadex LH-20 column chromatography. A new triterpene was obtained, and the structure was identified as 3β, 7β, 21β, 23-tetrahydroxyolean-12-ene-28-oic acid via 1D, 2D NMR techniques and HR-EI-MS analysis.

Key words: Rubiaceae, Neonauclea sessilifolia, Triterpene

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