Abstract:

The influence of sulfated polysaccharide(ESPS) isolated from marine algae Eucheuma striatum on the crystallization of calcium oxalate was investigated by means of scanning electron microscopy, infrared spectrum and X-ray diffraction. The results indicate that the addition of ESPS could inhibit the growth of calcium oxalate monohydrate(COM) and induce the formation of calcium oxalate dihydrate(COD) crystals. With the increase of ESPS mass concentration from 0 to 0.03 and 0.50 mg/mL, the percentage of COD crystals increased from 0 to 10% and 55%, respectively; the stabilization of the(101) face of COM crystals was strengthened, the(020) face was weakened; the morphology of COM crystals changes from threedimensional crystals to tetragonal slice crystals; and the size of both COM and COD crystals apparently become smaller. It is indicated that ESPS may be a potential inhibitor to calcium oxalate urinary stones.

Key words: Calcium oxalate; Algal polysaccharide; Urinary stone