Synthesis and Biological Activity of 3-Pyrimidylamino-pyrazoles

Abstract

Abstract: It has been reported that pyrazole and pyrimidine heterocyclic compounds maybe exhibit high pharmaceutical functions and pesticidal activity. A series of novel pyrimidylamino-pyrazole derivatives were synthesized and their biological activities were studied. All of the products were confirmed by ¹H NMR and elemental analysis, and some of them were characterized by IR and MS. The bioassy results indicated that some of the title compounds have a high fungicidal activity or herbicidal activity. In addition, the structure-activity relationship was discusses.

Key words: Pyrazole derivatives, Aminopyrimidine, Biological activity

CLC Number:

O626

TrendMD:

ZOU Xiao-Mao, WU Chao, ZHOU Chuan-Zheng, REN Xue-Ling, YANG Hua-Zheng . Synthesis and Biological Activity of 3-Pyrimidylamino-pyrazoles[J]. Chem. J. Chinese Universities, 2005, 26(3): 456.

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Synthesis and Biological Activity of 3-Pyrimidylamino-pyrazoles

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