Studies on Nano Ag2O2-PbO2 Modified Electrode-induced Cell Membranes and DNA Damage of E.coli

Chem. J. Chinese Universities ›› 2005, Vol. 26 ›› Issue (12): 2214.

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Studies on Nano Ag2O2-PbO2 Modified Electrode-induced Cell Membranes and DNA Damage of E.coli

GU Jing,ZHANG Wen,TANG Hui,JIN Li-Tong*, ZUO Yi, WU Zi-Rong

Department of Chemistry,East China Normal University,Shanghai 200062,China
College of Life Science,East China Normal University,Shanghai 200062,China

Received:2005-02-03 Online:1905-03-14 Published:1905-03-14
Contact: JIN Li-Tong;E-mail:ltjin@chem.ecnu.edu.cn

Abstract

Abstract:

The fabrication of a novel nano Ag₂O₂-PbO₂modified electrode is described.Hydroxide radical could be generated on the surface of the electrode at an optimized potential.Lipid peroxidate and transudatory protein were detected to show destruction of cell membrane of E.coli treated by Ag₂O₂-PbO₂modified electrode.DNA damage of E.coli was studied in detail with electrophoresis and DNA sequence determination.The results show that cracking of plasmid DNA and mutation of gene sequence could be induced by nano Ag₂O₂-PbO₂ modified electrode.

Key words: Nano Ag₂O₂-PbO₂modified electrode;E.coli;DNA damage, Nano AgO₂-PbO₂ modified electrode, E.coli, DNA damage

CLC Number:

O652

TrendMD:

GU Jing,ZHANG Wen,TANG Hui,JIN Li-Tong, ZUO Yi, WU Zi-Rong . Studies on Nano Ag2O2-PbO2 Modified Electrode-induced Cell Membranes and DNA Damage of E.coli[J]. Chem. J. Chinese Universities, 2005, 26(12): 2214.

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Studies on Nano Ag2O2-PbO2 Modified Electrode-induced Cell Membranes and DNA Damage of E.coli

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