New Constituents from Eleutherine americana

Abstract

Abstract: Three new constituents were isolated from Eleutherine americana Merr.et K.Heyne(Hong-cong)by means of silica gel,ODS column chromatography and high performance liquid chromatography(HPLC).They were identified as 9,9'-dihydroxy-8,8'- dimethoxy-1,1'-methyl-1H,1H'-\bi\funanyl]-3,3'-dione(1),6,8-dihydroxy-3,4-dimethoxy-1-methyl-anthraquinone-2-carboxylic acid methyl ester(2),2-acetyl-3,6,8-trihydroxy-1-methylanthraquinone(3) by physico-chemical propeties and spectral data,respectively.All three compounds showed weak activities against the growth of Pyricularia oryzae.The MMDC(Minimum morphological deformation mass concentration) was 145.8,50.2,124.8 μg/mL.Additionally,compound 2 also inhibited the proliferation of K562(human erythroleukemia) with IC₅₀ value of 49.1 μg/mL.

Key words: Eleutherine americana, Bioactivity, Pyricularia oryzae, Human erythroleukemia

CLC Number:

O629.9

TrendMD:

QIU Feng, XU Jin-Zhong, DUAN Wen-Juan, QU Ge-Xia, WANG Nai-Li, YAO Xin-Sheng. New Constituents from Eleutherine americana[J]. Chem. J. Chinese Universities, 2005, 26(11): 2057.

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New Constituents from Eleutherine americana

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