Abstract: The mechanisms of molecular motors are still unresolved problems. Based on our experiments on amino acids, the activated process of molecular motors was analyzed and original software using the method of penta-coordinated phosphorous structure was designed. Via the software, the hotspots from different molecular motors′ phosphorous activated area were obtained. It was found that the types of hotspots discovered with above methods were highly conserved. This founding provides new perspectives to study the intrinsic relationship of motion in molecular motors and also helps understanding the evolution of molecular motors.

Key words: Molecular motors, Penta-coordinated phosphorous structure analysis, Phosphorous activated area(PAA)